Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 30 of 57

COMPLETED NA

Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid

NCT03719755

COMPLETED

Pediatric NMOSD Observational Study

NCT03766347

TERMINATED NA

Pulmonary Rehabilitation in End-Stage Liver Disease

NCT03266575

COMPLETED

Coagulation Test Changes Associated With Acute Normovolemic Hemodilution in Cardiac Surgery

NCT03647644

COMPLETED NA

Augmenting Patching Treatment for Amblyopia With Physical Exercise

NCT03822806

COMPLETED NA

Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Pilot Study)

NCT03865329

COMPLETED

Thromboelastography-Guided Fluid Management in Spinal Surgery

NCT03999086

COMPLETED NA

Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy

NCT03341533

COMPLETED

Optical and Biochemical Biomarkers in Early Pancreatic Cancer

NCT03404661

COMPLETED NA

Performance and Nutrition Program for Athletes in Adaptive Sports

NCT03392155

COMPLETED Phase 1

Statins and CPAP in Adipose Tissue of OSA

NCT03308578

COMPLETED Phase 1

Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors

NCT03237390

COMPLETED NA

Cochlear Promontory Stimulation for Treatment of Tinnitus

NCT03759834

COMPLETED Phase 3

Enhancing Adaptations to Exercise

NCT03350906

COMPLETED NA

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

NCT03406975

COMPLETED Early Phase 1

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

NCT03276832

COMPLETED Phase 1

Mesenchymal Stem Cells Therapy in Patients With Recent Intracerebral Hemorrhage

NCT03371329

COMPLETED Phase 1

TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery

NCT03297710

COMPLETED Phase 3

Individualized Obesity Pharmacotherapy

NCT03374956

COMPLETED NA

Complications Associated With Primary Placement of Gastrostomy for Feeding

NCT05173935

COMPLETED

The TOGETHER Project - Heart

NCT03833050

COMPLETED Phase 2

Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

NCT03270085

COMPLETED Phase 1

Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer

NCT03012230

COMPLETED NA

Impact of Massage Therapy and Music Therapy on the Quality of Life of Hospice Patients

NCT03217682

COMPLETED NA

Connected Health Care in Exercise Program for Obesity

NCT03446235

COMPLETED Early Phase 1

Transthyretin Cardiac Amyloidosis in HFpEF

NCT03414632

COMPLETED NA

Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes

NCT03392441

COMPLETED NA

Transcutaneous Submandibular Gland Biopsy: Feasibility of Repeat Biopsy as a Progression Marker for Parkinson's Disease

NCT03359226

COMPLETED

Electrophysiological Comparison of mAP and mADM Using EMG

NCT03360825

COMPLETED Phase 2

New Technologies to Determine Carotid Plaque Vulnerability in Patients With Significant Carotid Plaques

NCT03335033

TERMINATED Phase 1

Use of Adipose Derived Regenerative Cells in Bilateral Femoral Head Osteonecrosis

NCT03269409

TERMINATED Phase 1

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

NCT03325101

COMPLETED NA

Characterization of Bile Acid Pathway in Obesity

NCT03341052

TERMINATED

Study to Assess Monoclonal B-Cell Lymphocytosis in Individuals With Chronic Hepatitis C

NCT06564051

COMPLETED Early Phase 1

Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides

NCT03281811

COMPLETED

Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

NCT03327623

COMPLETED

Assessment of Longitudinal Changes in Endothelial Function and Oxidative Stress in Normotensive Patients With ADPKD

NCT03493802

COMPLETED Phase 3

Staging Prostate Cancer With Hybrid C11-Choline PET/MR and mpMRI

NCT03404648

COMPLETED NA

Mobile Educations Effect on Pain Outcomes

NCT03301610

COMPLETED Phase 2

TAS-102 in Treating Advanced Biliary Tract Cancers

NCT03278106

COMPLETED

Wound Necrosis in Lower Extremity Surgery

NCT03351387

COMPLETED Phase 1

Stem Cell Coated Fistula Plug in Patients With Crohn's RVF

NCT03220243

TERMINATED

Ultrasound-Guided Costoclavicular Block in Patients With a BMI > 30

NCT03314948

COMPLETED NA

Engineering Gut Microbiome to Target Breast Cancer

NCT03358511

COMPLETED NA

Changes in Intestinal Permeability 4 Hours After Gluten Challenge

NCT03288831

COMPLETED NA

Music Therapy Intervention to Reduce Caregiver Distress at the End of Life

NCT03322228

TERMINATED NA

EPAD Monitoring of Patients Undergoing Robotic Assisted Laparoscopic Genitourinary Surgery

NCT03319407

COMPLETED NA

Efficacy of Penile Traction Therapy Using a Novel Device

NCT03389854

COMPLETED Phase 4

Pneumococcal Vaccines in Patients With Asthma

NCT03260790

COMPLETED

Mucosal Impedance Balloon in Diagnosis and Treatment of Eosinophilic Esophagitis (EoE)

NCT02995395

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.