Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 25 of 57

COMPLETED NA

Digital Home-Exercise Therapy Application For Patients With Non-Surgical Knee Injuries

NCT04323267

COMPLETED NA

Effectiveness of Nurse-based Care Coordination on Readmissions Among Primary Care Patients: a Stepped Wedge Cluster Randomized Trial

NCT04224220

COMPLETED NA

Remote Self-training Program for Patients With Postural Orthostatic Tachycardia Syndrome

NCT04603157

COMPLETED NA

Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity

NCT03836547

COMPLETED NA

Connecting Alaska Native People to Quit Smoking

NCT03645941

COMPLETED Phase 1

Fingolimod in Preventing Paclitaxel-Associated Neuropathy in Patients With Breast Cancer

NCT03941743

COMPLETED NA

Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia

NCT04378218

COMPLETED NA

A Comparison Study of Three Standard Elbow Wrist Hand Orthoses to Limit Forearm Rotation

NCT04130425

COMPLETED NA

Stories for Change: Digital Storytelling for Diabetes Self-Management Among Somali Adults

NCT04266054

COMPLETED NA

Web-based CBT for Insomnia Patients With Fibromyalgia

NCT03922867

COMPLETED Phase 2

Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

NCT03852537

COMPLETED NA

Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction

NCT04136288

COMPLETED

Genetic Variants in Nicotinamide Adenine Dinucleotide (NAD) Synthesis Pathway

NCT03799705

COMPLETED Phase 4

Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients

NCT04054999

COMPLETED

Bispectral Index: A Comparison of Bifrontal Montage Agreement

NCT04062240

COMPLETED NA

Psychotherapy (Accelerated Resolution Therapy) for Cancer Related Trauma and Distress

NCT04436835

COMPLETED

NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients

NCT04231591

TERMINATED NA

Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress Testing

NCT04019613

TERMINATED Early Phase 1

Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients

NCT04213794

COMPLETED Phase 1

Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective Tissue Disorders (CTD)

NCT03929120

TERMINATED NA

Arterial Stiffness and Atrial Fibrillation

NCT04160663

COMPLETED NA

Health Coaching to Improve Self-Management in Thoracic Transplant Candidates

NCT03150095

TERMINATED Phase 1

Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

NCT03840343

COMPLETED Phase 2

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

NCT04072445

COMPLETED Early Phase 1

Comparison of Three Methods for Early Detection of Breast Cancer

NCT03954015

COMPLETED

Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

NCT04262310

COMPLETED NA

Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease

NCT04118985

TERMINATED NA

Patient Experience Comparing Tonic Vs. Burst Spinal Cord Stimulation For Chronic Pain

NCT04159753

COMPLETED

Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Following Magnetic Resonance Imaging

NCT04151953

COMPLETED

Large-Scale Metabolomic Profiling for the Diagnosis of Inborn Errors of Metabolism

NCT04201067

TERMINATED NA

Discharged With Indwelling Chest Tube and Valve

NCT03943511

COMPLETED

A Study to Evaluate Unintended Prolonged Opioid Use

NCT04024397

COMPLETED

Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

NCT04166539

COMPLETED NA

Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

NCT04120025

COMPLETED

The Role of Mucosal Microbiome in Recurrence of Clostridioides Difficile Infection

NCT04675723

COMPLETED

Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

NCT04183218

COMPLETED NA

Neuromuscular Blocking Agents Utilized During Perioperative Hypersensitivity Evaluation

NCT04046731

COMPLETED NA

Negative Predictive Value and NIC of Beta-Lactam Antibiotics.

NCT04126096

COMPLETED NA

Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging

NCT03818802

TERMINATED

Automated Myocardial Performance Index Using Samsung HERA W10

NCT04140669

COMPLETED

Breath Analysis Based Disease Biomarkers

NCT04341012

TERMINATED Phase 4

Budesonide in Patients With Immune Mediated Enteropathies

NCT03866538

TERMINATED NA

Bandage Contact Lens Application for the Management of Corneal Abrasion

NCT04159714

COMPLETED Phase 2

Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia

NCT03941288

COMPLETED

Evaluating Sexual Function in Women Undergoing a Radical Cystectomy for Bladder Cancer

NCT05399004

TERMINATED Phase 4

Liposomal Bupivacaine in Vaginal Hysterectomy

NCT03907033

COMPLETED Phase 4

Lofexidine for Adults Undergoing Lumbar Spine Surgery

NCT04126083

COMPLETED

The Characteristics and Role of Mucosal Microbiome After Treatment of Clostridioides Difficile Infection

NCT04668014

COMPLETED NA

Psychological Support Based on Positive Suggestions (PSBPS) on Mental Health Morbidity and Cognitive Function

NCT04045210

COMPLETED

Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer

NCT04156126

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.