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NCT04054999 · ClinicalTrials.gov registry record · Phase 4
Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients
A Phase 4 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 19
- Enrollment target
NCT04054999: Completed Phase 4 study, sponsored by Mayo Clinic.
NCT04054999 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 19 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04054999, a Phase 4 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 19 participants
- Enrollment target
Study Summary
This study will evaluate if Hydroxocobalamin may be a new and possibly superior treatment for refractory vasoplegic syndrome during liver transplant surgery.
Primary Outcome
SVR refers to the resistance to blood flow offered by all of the systemic vasculature, excluding the pulmonary vasculature. Measured during surgery at 15, 30, 60, 90 and 120 minutes after initiation of treatment.
Interventions
- DRUG Hydroxocobalamin
- DRUG Methylene Blue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2019-11-30 |
| Est. Completion | 2024-02-27 |
| Phase | Phase 4 |
What the finished NCT04054999 record still lists
NCT04054999 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Hydroxocobalamin is the first listed.
NCT04054999 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04054999 about?
NCT04054999 is a clinical study titled "Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients". This study will evaluate if Hydroxocobalamin may be a new and possibly superior treatment for refractory vasoplegic syndrome during liver transplant surgery.
What is the current status of trial NCT04054999?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 19 participants. The study started on 2019-11-30. Estimated completion is 2024-02-27.
What interventions are being tested in trial NCT04054999?
The interventions under investigation include: Hydroxocobalamin (DRUG), Methylene Blue (DRUG).
Who is sponsoring clinical trial NCT04054999?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04054999's enrollment target sits among peer trials
19 1834th of 2000 higher than 159 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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