Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 26 of 57

COMPLETED NA

Low-Cost Tool for Compliance and Treatment-Tracking of Low Back Pain Patients

NCT03478007
COMPLETED NA

Comprehensive Genetic Assessment, Risk and Education in a Mammography Pilot

NCT04002986
COMPLETED NA

Artificial Intelligence/Machine Learning Modeling on Time to Palliative Care Review in an Inpatient Hospital Population

NCT03976297
TERMINATED

Optimal Endoscopic Suturing Pattern for Esophageal Stent Fixation

NCT04007692
COMPLETED NA

ALateral Flow Assay to Detect QSOX1 Peptide in Patients With or at Risk for Pancreatic Cancer

NCT04064034
COMPLETED Early Phase 1

Mepolizumab for the Treatment of Chronic Spontaneous Urticaria

NCT03494881
COMPLETED

Myocardial Injury Following Elective Direct Current Cardioversion for Atrial Arrhythmias

NCT04151966
COMPLETED Phase 4

Envarsus XR Compared to Immediate Release Tacrolimus

NCT03979365
COMPLETED Phase 4

Pharmacogenomics and Pharmacometabolomics of Acamprosate Treatment Outcome

NCT03818191
COMPLETED Phase 1

Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee

NCT03940950
COMPLETED Early Phase 1

Impact of Ascorbic Acid Treatment on the Development and Treatment of Vasodilation in Cardiac Surgery

NCT03744702
COMPLETED NA

ECG AI-Guided Screening for Low Ejection Fraction

NCT04000087
TERMINATED Phase 1

Treating Acute Pancreatitis With Dabigatran, a Pilot Study

NCT03807856
COMPLETED Early Phase 1

A Pilot Study on the Use of Platelet Rich Plasma (PRP) for Facial and Hand Skin Rejuvenation

NCT03647917
COMPLETED Phase 4

Use of Sublingual Tacrolimus in Adult Blood and Marrow Transplant Patients

NCT04041219
TERMINATED Phase 2

Rifaximin in Patients With Diabetic Gastroparesis

NCT04254549
COMPLETED NA

Assess Screening for Diabetic Retinopathy Using Retinal Camera in Family Medicine Clinic

NCT03828890
TERMINATED Phase 1

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

NCT03865212
COMPLETED

Functional Predictive Value of Collective Outcome Measure(s) Status Post Total Hip/Knee Arthroplasty

NCT03933969
COMPLETED NA

Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)

NCT04019314
COMPLETED Early Phase 1

Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer

NCT04067960
COMPLETED Phase 1

Safety of Intra-Articular Sc-rAAV2.5IL-1Ra in Subjects With Moderate Knee OA

NCT02790723
COMPLETED NA

Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population

NCT03954964
COMPLETED

A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache

NCT06132529
COMPLETED NA

Awake vs. Asleep Craniotomy for Non-eloquent Gliomas

NCT03621748
COMPLETED Phase 3

Guided Meditation During Radiotherapy.

NCT04303013
COMPLETED

Time Longitudinal Study of the Microbiome in Colorectal Cancer Subjects

NCT03951792
COMPLETED Early Phase 1

Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy

NCT03943498
COMPLETED

Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)

NCT03718494
COMPLETED NA

Implementing a Low FODMAP Diet in Irritable Bowel Syndrome Patients

NCT03948854
COMPLETED NA

Study Title: Food Rx

NCT03937934
TERMINATED NA

Telemedicine Follow-up for Bariatric Surgery Patients: What Do Patients Prefer

NCT04784286
COMPLETED Phase 2

Assess the Efficacy and Safety of Exenatide SR for the Prevention of Diabetes After Kidney Transplantation

NCT03961256
COMPLETED NA

Minimally Invasive Pericardiotomy as a New Treatment for Heart Failure

NCT03923673
COMPLETED Phase 1

Nab-paclitaxel/Rituximab-coated Nanoparticle AR160 in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, LS1681 Trial

NCT03003546
TERMINATED Phase 2

Vitamin B12a Vasoplegic Syndrome

NCT03735316
COMPLETED

Learning Lab for Diagnostic Fidelity

NCT03865303
COMPLETED Phase 1

Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma

NCT03829020
COMPLETED Early Phase 1

Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty

NCT03845881
COMPLETED

In-person Focus Groups in the Management of Urinary Incontinence in Women

NCT05395793
COMPLETED NA

Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial

NCT03892967
COMPLETED Phase 2

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

NCT03778294
COMPLETED Phase 4

Imaging the Migraine Brain Pre- and Post-Erenumab

NCT03773562
COMPLETED NA

Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor

NCT03875404
COMPLETED NA

Short Messaging Service Program to Help Quit Smoking During Perioperative Period.

NCT03839043
COMPLETED Phase 2

Oophorectomy, Estrogen Therapy and Cardiovascular Disease Risk in Young Women

NCT03815929
COMPLETED Phase 2

Metformin Effect on Brain Function in Insulin Resistant Elderly People

NCT03733132
TERMINATED NA

Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin Sensitivity

NCT03494868
COMPLETED NA

Spanish Translation and Cultural Adaptation of the Memory Support System

NCT03933085
COMPLETED

Quality of Life Assessed With the PAH SYMPACT Questionnaire

NCT03905421
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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

Therapeutic Areas

Healthy 36
Malignant Solid Neoplasm 35
Obesity 31
Breast Cancer 25
Breast Carcinoma 21
Hematopoietic and Lymphatic System Neoplasm 20
Hematopoietic and Lymphoid System Neoplasm 12
Heart Failure 11
Cancer 11
Prostate Carcinoma 9

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.