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NCT04156126 · ClinicalTrials.gov registry record

Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer

A clinical trial, sponsored by Mayo Clinic.

Completed
Registry status
56
Enrollment target

NCT04156126: Completed study, sponsored by Mayo Clinic.

NCT04156126 is a clinical trial that has completed, run by Mayo Clinic. The registered enrollment target is 56 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04156126 has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
56 participants
Enrollment target

Study Summary

Pregnancy is a unique period which requires alterations in the immune system to allow for tolerance of a haploidentical fetus. The goal of this study is to measure maternal blood levels of proteins known to promote immune tolerance in early implantation and pregnancy to look for associations between tolerance, miscarriage and failed embryo transfer. Establishing predictive factors of miscarriage and failed in vitro fertilization could have implications for a large portion of couples and serve to guide current and future family planning efforts.

Primary Outcome

Tolerance markers galectin-9, IL-4 and VEGF (-A,-B,-C,-D) will be measured for their concentration in maternal blood in women who conceived naturally, as determined by experimental standard curves.

Interventions

  • OTHER Blood Collection

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2019-08-23
Est. Completion 2024-06-01
Mayo Clinic

2,844 total trials

What the finished NCT04156126 record still lists

NCT04156126 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Blood Collection is the first listed.

NCT04156126 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04156126 about?

NCT04156126 is a clinical study titled "Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer". Pregnancy is a unique period which requires alterations in the immune system to allow for tolerance of a haploidentical fetus. The goal of this study is to measure maternal blood levels of proteins known to promote immune tolerance in early implantation and pregnancy to look for associations between...

What is the current status of trial NCT04156126?

This trial is currently completed. The enrollment target is 56 participants. The study started on 2019-08-23. Estimated completion is 2024-06-01.

What interventions are being tested in trial NCT04156126?

The interventions under investigation include: Blood Collection (OTHER).

Who is sponsoring clinical trial NCT04156126?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT04156126, the US trial registry maintained by the National Library of Medicine. NCT04156126 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.