Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 24 of 57

COMPLETED Phase 1

Trial of Indomethacin in Chronic Pancreatitis

NCT04207060

COMPLETED NA

Resilient Living Program for Patients With Advanced Cancer and Their Caregivers

NCT04480008

COMPLETED NA

Community Paramedicine Program to Improve Diabetes Care Quality, Equity, and Outcomes

NCT04385758

TERMINATED Phase 2

Antihistamines in Eosinophilic Esophagitis

NCT04248712

COMPLETED Phase 4

Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

NCT04258631

COMPLETED NA

Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes

NCT04073394

COMPLETED NA

Handheld Dynamometer During Awake Craniotomy Pilot

NCT04742231

COMPLETED NA

Ultrasound Guided - Incisionless Threaded Carpal Tunnel Release

NCT04101955

TERMINATED NA

Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear

NCT04442464

COMPLETED Phase 1

Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study

NCT04456140

COMPLETED

Fractures and Bone Disease in Living Kidney Donors

NCT04810884

TERMINATED

Feasibility in the Prophylaxis of Radiation Dermatitis Severity

NCT04715386

COMPLETED

Grid Therapy for Tumors of the Head, Neck, Thorax, Abdomen, Pelvis and Extremities.

NCT04549246

COMPLETED NA

Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation

NCT04129411

COMPLETED NA

Wellness Coaching for Caregivers of Thoracic Transplant Candidates

NCT04245228

COMPLETED Early Phase 1

PSMA PET/MRI or PSMA PET/CT for Evaluation of Liver Cancer

NCT04310540

TERMINATED Phase 2

Gemcitabine for the Prevention of Intravesical Recurrence of Urothelial Cancer in Patients With Upper Urinary Tract Urothelial Cancer Undergoing Radical Nephroureterectomy, GEMINI Study

NCT04398368

COMPLETED Phase 4

Anti-Obesity Phentermine-Topiramate Extended Release Pharmacotherapy vs Placebo Among Patients Using a Wearable Activity Tracker

NCT04408586

COMPLETED

Feasibility of Rapid COVID-19 Testing in Disadvantaged Populations

NCT04558307

COMPLETED Phase 4

Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction

NCT04417998

COMPLETED NA

Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection

NCT04301934

COMPLETED NA

Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection

NCT04694638

COMPLETED

Pain Management Intervention Preparatory to a Future Pragmatic Trial

NCT04336592

COMPLETED

Risks of COVID19 in the Pregnant Population

NCT04379284

COMPLETED NA

Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers

NCT04383587

COMPLETED Phase 1

Allogeneic BM-MSCs in Patients with Lumbar Facet Arthropathy

NCT04410731

COMPLETED Phase 2

Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer

NCT04294225

COMPLETED NA

Comparing MRI to CT on Pediatric Craniosynostosis.

NCT04704284

COMPLETED

Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry

NCT04323787

TERMINATED NA

Exploring Psychometric Properties of a New Version of the 6MWT in the Acute Stroke Population

NCT04515693

COMPLETED NA

Cryotherapy for the Prevention of Taxane-Induced Sensory Neuropathy of the Hands and Feet in Breast Cancer Patients

NCT04256512

TERMINATED

Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

NCT04316468

COMPLETED Phase 1

Non-intrusive Detection of Temporary Neurologic Impairment By Opioids

NCT04223609

COMPLETED

Ultrasonic Perfusion Estimation in Calf Muscle

NCT04755335

COMPLETED Early Phase 1

Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

NCT04217694

COMPLETED

Microbiome and Immunologic Analysis - Women With Endometriosis

NCT04159740

COMPLETED Phase 2

Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

NCT03695471

COMPLETED NA

Improving the Quality of Dementia Care Through Innovative Redesign of the Memory Care Environment

NCT04350060

COMPLETED NA

The FAITH! Trial: A mHealth Intervention to Improve Cardiovascular Health Among African-Americans

NCT03777709

COMPLETED Phase 1

Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates

NCT04474184

COMPLETED NA

Intravascular Volume Expansion to Neuroendocrine-Renal Function Profiles in Chronic Heart Failure

NCT04156854

COMPLETED NA

Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue

NCT04234295

COMPLETED NA

Pilot Social Network Weight Loss Intervention

NCT04273503

COMPLETED

Copeptin as a Biomarker for Central Diabetes Insipidus Development Following Pituitary Surgery

NCT04369703

COMPLETED NA

Augmented Human Intelligence in Major Depressive Disorder

NCT04355650

COMPLETED NA

Effect of Coaching on Surgeon Well-Being, Job Satisfaction, & Fulfillment

NCT04235751

COMPLETED NA

Evaluating the Safety and Effectiveness of the Flex Robotic System for the Surgical Removal of Colorectal Lesions

NCT05674123

TERMINATED Phase 2

Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer

NCT03979508

COMPLETED NA

Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases

NCT03911856

COMPLETED Phase 1

Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)

NCT04047810

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.