Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,816 of 2,102 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,844 total, page 22 of 57
A Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers
NCT04809883
CGM Use in COVID19 Patients (Infection With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2))
NCT04756141
Oral Glucose Tolerance Testing Using Candy for Cystic Fibrosis
NCT04579939
68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer
NCT04762888
Dapagliflozin (DAPA) Effects in HFpEF
NCT04730947
Letrozole in Patients With Hepatopulmonary Syndrome
NCT04577001
Changes in Gene Transcription and Immunophenotypes Following Mepolizumab Treatment for Asthma
NCT05002621
A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones
NCT04387617
COVID-19 Vaccination in Rheumatic Disease Patients
NCT04839315
Community-Engaged Bidirectional Pandemic Crisis and Emergency Risk Communication With COVID-19 Vaccine Messages to Minority Populations
NCT04765839
Comparison of Compact 3T, Conventional 3T, and 7T Scanners Using Task Based and Resting State fMRI
NCT04172428
Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects
NCT04724304
A Study to Detect Progression of Mass Effect From Unilateral Brain Lesions
NCT04745884
BeWell360-CG Care Model: Health and Wellness Coaching to Support Caregivers of Patients Living With Advanced Lung Cancers
NCT05640765
Medical Grade, Smartphone-based, Fetal Heart Rate Monitor for Outpatient Use
NCT04232215
Longitudinal Study Evaluating Recovery After Scheduled Cesarean Delivery
NCT04462107
Cios Mobile 3D Spin for Robotic Bronchoscopy
NCT04740047
Stretching and Musculoskeletal Pain
NCT04617379
A Study to Evaluate Effects of Gargle Phonation in Voice
NCT04766658
Immunogenicity and Safety of Commercially Available Vaccines Against SARS-CoV-2 (COVID-19) in Patients With Hematologic Malignancies
NCT04748185
Determining The Impact Of Distance Reiki On Patient Reported QOL And Immunity Among Multiple Myeloma Patients
NCT04783038
Evaluation of the Veriton SPECT/CT System
NCT04722185
Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning
NCT06409000
First Responder Resiliency Program During COVID-19
NCT04536376
Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face
NCT04523961
Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH
NCT04098250
Continuous Glucose Monitoring in Hospitalized Patients With Diabetes Mellitus
NCT04653454
A Study to Assess Virtual Reality by Healthcare Providers: A Pilot Study
NCT04622527
Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer
NCT04493060
A Study to Assess the Effect of Psyllium vs. Wheat Dextrin on Glycemic Control and Inflammatory Markets in Diabetes Mellitus 2
NCT04547790
Low-Intensity Blood Flow Restriction Training as a Pre-Operative Rehabilitative Modality to Improve Post-Operative Outcomes for ACL Reconstruction
NCT04302558
Stress Management and Resiliency Training for Depression vs Treatment as Usual in the Treatment of Major Depression
NCT04388748
Sleep in Women With Bilateral Salpingo-Oophorectomy
NCT04565158
Mayo Posture Positivity Power Program for Active and Aging Individuals in Communities
NCT04681794
Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma
NCT04581382
A Study to Evaluate Rapid Throughput Screening for Human COVID-19 Infection
NCT04725097
Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy
NCT04650204
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
NCT04342975
Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Study 2)
NCT04521608
The Impact of Training With Whole Body-EMS
NCT04288154
Great Posture, Great Health
NCT04630561
Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder
NCT04610827
Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy
NCT04620369
A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD
NCT05777161
Daratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Study
NCT04230304
Mayo Designed Soft Tissue Ultrasound-Detectable Marker
NCT04674852
Batch Enrollment for AI-Guided Intervention to Lower Neurologic Events in Unrecognized AF
NCT04208971
Deep Venous Thrombus Characteristics and Venous Dynamics With Subsequent Thrombus Resolution and Post-thrombotic Syndrome
NCT04597138
Efficacy of Percutaneous SPG Block in Aneurysmal SAH
NCT04331938
Tonal Exercise System to Improve Short and Long Term Low Back Pain
NCT04543396
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Mayo Clinic: open-pipeline peers nationwide
Peers matched on 2,844 registered trials and 19% open enrollment, not the therapeutic-area sidebar.
Mayo Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,844 trials (± recruiting share)
- M.D. Anderson Cancer Center · 2,692 trials · 20% recruiting
- National Cancer Institute (NCI) · 3,257 trials · 10% recruiting
- Massachusetts General Hospital · 2,032 trials · 17% recruiting
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
Sponsors near 19% open enrollment (± trial volume)
- University of South Carolina · 19% recruiting · 157 trials
- Vanderbilt University Medical Center · 19% recruiting · 677 trials
- MemorialCare Health System · 19% recruiting · 21 trials
- University of North Texas Health Science Center · 19% recruiting · 21 trials
Related
What to do with this Mayo Clinic page
2,844 registered trials is a research-attention snapshot, not an endorsement of Mayo Clinic or any single study.
- 544 of Mayo Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition Mayo Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Mayo Clinic pipeline card: 2,844 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.