Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 22 of 57

COMPLETED

A Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers

NCT04809883

COMPLETED NA

CGM Use in COVID19 Patients (Infection With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2))

NCT04756141

COMPLETED NA

Oral Glucose Tolerance Testing Using Candy for Cystic Fibrosis

NCT04579939

COMPLETED Phase 2

68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer

NCT04762888

COMPLETED Phase 2

Dapagliflozin (DAPA) Effects in HFpEF

NCT04730947

TERMINATED Phase 2

Letrozole in Patients With Hepatopulmonary Syndrome

NCT04577001

COMPLETED

Changes in Gene Transcription and Immunophenotypes Following Mepolizumab Treatment for Asthma

NCT05002621

COMPLETED Phase 2

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

NCT04387617

TERMINATED Early Phase 1

COVID-19 Vaccination in Rheumatic Disease Patients

NCT04839315

COMPLETED NA

Community-Engaged Bidirectional Pandemic Crisis and Emergency Risk Communication With COVID-19 Vaccine Messages to Minority Populations

NCT04765839

COMPLETED

Comparison of Compact 3T, Conventional 3T, and 7T Scanners Using Task Based and Resting State fMRI

NCT04172428

COMPLETED NA

Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

NCT04724304

TERMINATED NA

A Study to Detect Progression of Mass Effect From Unilateral Brain Lesions

NCT04745884

COMPLETED NA

BeWell360-CG Care Model: Health and Wellness Coaching to Support Caregivers of Patients Living With Advanced Lung Cancers

NCT05640765

COMPLETED NA

Medical Grade, Smartphone-based, Fetal Heart Rate Monitor for Outpatient Use

NCT04232215

COMPLETED

Longitudinal Study Evaluating Recovery After Scheduled Cesarean Delivery

NCT04462107

COMPLETED

Cios Mobile 3D Spin for Robotic Bronchoscopy

NCT04740047

COMPLETED NA

Stretching and Musculoskeletal Pain

NCT04617379

COMPLETED NA

A Study to Evaluate Effects of Gargle Phonation in Voice

NCT04766658

COMPLETED

Immunogenicity and Safety of Commercially Available Vaccines Against SARS-CoV-2 (COVID-19) in Patients With Hematologic Malignancies

NCT04748185

COMPLETED NA

Determining The Impact Of Distance Reiki On Patient Reported QOL And Immunity Among Multiple Myeloma Patients

NCT04783038

COMPLETED NA

Evaluation of the Veriton SPECT/CT System

NCT04722185

COMPLETED

Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning

NCT06409000

COMPLETED NA

First Responder Resiliency Program During COVID-19

NCT04536376

COMPLETED Phase 2

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

NCT04523961

COMPLETED Phase 2

Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH

NCT04098250

COMPLETED NA

Continuous Glucose Monitoring in Hospitalized Patients With Diabetes Mellitus

NCT04653454

COMPLETED NA

A Study to Assess Virtual Reality by Healthcare Providers: A Pilot Study

NCT04622527

COMPLETED Phase 2

Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer

NCT04493060

COMPLETED NA

A Study to Assess the Effect of Psyllium vs. Wheat Dextrin on Glycemic Control and Inflammatory Markets in Diabetes Mellitus 2

NCT04547790

COMPLETED NA

Low-Intensity Blood Flow Restriction Training as a Pre-Operative Rehabilitative Modality to Improve Post-Operative Outcomes for ACL Reconstruction

NCT04302558

COMPLETED NA

Stress Management and Resiliency Training for Depression vs Treatment as Usual in the Treatment of Major Depression

NCT04388748

COMPLETED

Sleep in Women With Bilateral Salpingo-Oophorectomy

NCT04565158

COMPLETED NA

Mayo Posture Positivity Power Program for Active and Aging Individuals in Communities

NCT04681794

COMPLETED Early Phase 1

Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma

NCT04581382

TERMINATED

A Study to Evaluate Rapid Throughput Screening for Human COVID-19 Infection

NCT04725097

TERMINATED Phase 4

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

NCT04650204

COMPLETED Phase 2

Protection From Acute Kidney Injury (AKI) With Basis™ Treatment

NCT04342975

COMPLETED NA

Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Study 2)

NCT04521608

COMPLETED NA

The Impact of Training With Whole Body-EMS

NCT04288154

COMPLETED NA

Great Posture, Great Health

NCT04630561

TERMINATED Phase 4

Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder

NCT04610827

COMPLETED Phase 3

Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy

NCT04620369

COMPLETED NA

A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD

NCT05777161

TERMINATED Phase 2

Daratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Study

NCT04230304

COMPLETED NA

Mayo Designed Soft Tissue Ultrasound-Detectable Marker

NCT04674852

COMPLETED

Batch Enrollment for AI-Guided Intervention to Lower Neurologic Events in Unrecognized AF

NCT04208971

COMPLETED

Deep Venous Thrombus Characteristics and Venous Dynamics With Subsequent Thrombus Resolution and Post-thrombotic Syndrome

NCT04597138

COMPLETED Phase 1

Efficacy of Percutaneous SPG Block in Aneurysmal SAH

NCT04331938

COMPLETED NA

Tonal Exercise System to Improve Short and Long Term Low Back Pain

NCT04543396

← Previous Page 22 of 57 Next →

Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.