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NCT04342975 · ClinicalTrials.gov registry record · Phase 2

Protection From Acute Kidney Injury (AKI) With Basis™ Treatment

A Phase 2 study of AKI, sponsored by Mayo Clinic.

Completed
Registry status
Phase 2
Development phase
54
Enrollment target
1
Study location

NCT04342975 is a Phase 2 study of AKI that has completed, run by Mayo Clinic. The registered enrollment target is 54 participants, below the 78-participant average among 4 other AKI trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04342975, a Phase 2 study of AKI, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 2
Development phase
54 participants
Enrollment target
1
Study location

Study Summary

This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in preventing acute kidney injury (AKI) in patients undergoing complex aortic aneurysm repair and open aortic arch reconstruction.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Nicotinamide Riboside + Pterostilbene

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2020-12-01
Est. Completion 2024-03-14
Phase Phase 2

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT04342975

The ClinicalTrials.gov registry entry for NCT04342975 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 78-participant average among 4 other AKI trials with a reported enrollment target (31% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with AKI appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04342975 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT04342975 about?

NCT04342975 is a clinical study titled "Protection From Acute Kidney Injury (AKI) With Basis™ Treatment". This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in preventing acute kidney injury (AKI) in patients undergoing complex aortic an...

What is the current status of trial NCT04342975?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 54 participants. The study started on 2020-12-01. Estimated completion is 2024-03-14.

What conditions does trial NCT04342975 study?

This clinical trial studies the following conditions: AKI.

What interventions are being tested in trial NCT04342975?

The interventions under investigation include: Placebo (DRUG), Nicotinamide Riboside + Pterostilbene (DRUG).

Who is sponsoring clinical trial NCT04342975?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04342975 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.