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NCT04523961 · ClinicalTrials.gov registry record · Phase 2
Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 22
- Enrollment target
NCT04523961: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT04523961 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 22 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04523961, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 22 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.
Primary Outcome
Participants were asked to rate their pain using the self-reported visual analog scale (VAS). The VAS uses a scale of 0 = no pain to 10 = worst pain. Total scores range from 0 - 10, with lower scores indicating lower pain and higher scores indicating greater pain.
Interventions
- DRUG 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion
- DRUG 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2021-01-08 |
| Est. Completion | 2025-02-19 |
| Phase | Phase 2 |
What the finished NCT04523961 record still lists
NCT04523961 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion is the first listed.
NCT04523961 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04523961 about?
NCT04523961 is a clinical study titled "Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face". The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.
What is the current status of trial NCT04523961?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2021-01-08. Estimated completion is 2025-02-19.
What interventions are being tested in trial NCT04523961?
The interventions under investigation include: 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion (DRUG), 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion (DRUG).
Who is sponsoring clinical trial NCT04523961?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04523961's enrollment target sits among peer trials
22 1790th of 2000 higher than 207 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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