Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04839315 · ClinicalTrials.gov registry record · Early Phase 1

COVID-19 Vaccination in Rheumatic Disease Patients

A Early Phase 1 study, sponsored by Mayo Clinic.

Terminated
Registry status
Early Phase 1
Development phase
58
Enrollment target

NCT04839315: Clinical Trial Early Phase 1 study, sponsored by Mayo Clinic.

NCT04839315 is a Early Phase 1 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 58 participants, roughly in line with the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT04839315, a Early Phase 1 study, was terminated before completion, sponsored by Mayo Clinic.

TERMINATED
Registry status
Early Phase 1
Development phase
58 participants
Enrollment target

Study Summary

The research is being done to study the immune responses to COVID-19 vaccination in patients with rheumatic diseases.

Primary Outcome

We aim to examine SARS-Cov2 specific antibody, and autoantibody generation

Interventions

  • BIOLOGICAL mRNA COVD19 vaccine

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2021-02-15
Est. Completion 2022-02-09
Phase Early Phase 1
Mayo Clinic

2,844 total trials

Why NCT04839315 stopped before completion

NCT04839315 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, roughly in line with the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which mRNA COVD19 vaccine is the first listed.

NCT04839315 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04839315 about?

NCT04839315 is a clinical study titled "COVID-19 Vaccination in Rheumatic Disease Patients". The research is being done to study the immune responses to COVID-19 vaccination in patients with rheumatic diseases.

What is the current status of trial NCT04839315?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 58 participants. The study started on 2021-02-15. Estimated completion is 2022-02-09.

What interventions are being tested in trial NCT04839315?

The interventions under investigation include: mRNA COVD19 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT04839315?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04839315's enrollment target sits among peer trials

58 441st of 2000 higher than 1,555 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03587844 · 58 participants · Phase 2

    Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients

  • NCT03630991 · 58 participants · Phase 1

    Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

  • NCT03949855 · 58 participants · Phase 2

    Belimumab With Rituximab for Primary Membranous Nephropathy

  • NCT04069273 · 58 participants · Phase 2

    Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04839315, the US trial registry maintained by the National Library of Medicine. NCT04839315 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.