Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 23 of 57

COMPLETED NA

Examining Behaviors of Teachers of Invasive Bedside Procedures Using an Eye Tracking Device

NCT04235790

TERMINATED NA

TENS Used for Pain Management During Office Cystoscopy Botox Injections

NCT04448171

TERMINATED Phase 2

Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer

NCT04396535

COMPLETED

Provider Perspectives on Beta-lactam Therapeutic Drug Monitoring Programs in the Critically Ill

NCT04755777

COMPLETED NA

A Multi-Center Clinical Trial to Determine the Impact of a Mobile Health Application on Rheumatoid Arthritis Shared Decision Making

NCT03773471

COMPLETED Phase 4

HPV Educational Intervention to Increase Acceptance and Completion of Free HPV Vaccination Among Underserved Adults

NCT04474821

COMPLETED NA

Non-pharmacological Pain Management After Surgery

NCT04570371

COMPLETED NA

Home Telemonitoring In Patients After Myocardial Infarction

NCT04664881

COMPLETED NA

Operative Curriculum Gallbladder Surgery

NCT04691206

COMPLETED NA

Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors

NCT04421040

COMPLETED NA

Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown Primaries

NCT04489212

COMPLETED

Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis

NCT04886349

COMPLETED

Prospective Evaluation of Biliary Tissue Sampling With ERCP

NCT04572711

TERMINATED Phase 1

Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons

NCT04286529

TERMINATED NA

A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System for Chronic Subdural Evacuation

NCT04502745

COMPLETED Phase 1

Automated Retinal Image Analysis System (EyeQuant) for Computation of Vascular Biomarkers

NCT04567745

COMPLETED NA

Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

NCT04551339

COMPLETED

Predicting Placental Pathologies by Ultrasound Imaging

NCT04506970

TERMINATED

Nitrates and IL-8 in Barrett's Esophagus

NCT04642690

COMPLETED Phase 1

Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer

NCT04535323

COMPLETED

The ICE WATCHMAN Trial

NCT04569734

COMPLETED Phase 2

Acamprosate Safe to Use in Individuals With Liver Disease.

NCT04287920

COMPLETED NA

Primary Care Referrals to Community-based Lifestyle Programs for Management of Obesity

NCT04433806

TERMINATED Phase 2

Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer

NCT04249622

COMPLETED

Rapid Diagnostic Supporting Antimicrobial Stewardship in Patients With Pneumonia

NCT05937126

COMPLETED

Investigate the Mechanisms, Predictors, and Prevention of Persistent Post-Traumatic Headache

NCT04369729

COMPLETED NA

Consent Forms in Cancer Research: Examining the Effect of Length on Readability

NCT04548063

COMPLETED Phase 1

"Prescribing" Exercise to Cancer Patients At High-Risk for Falls

NCT04236154

COMPLETED NA

Molecular Mechanisms of Exercise Benefits to Insulin Resistant People

NCT04158375

COMPLETED NA

A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic Method

NCT04752098

COMPLETED NA

Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes

NCT04510272

COMPLETED Phase 2

Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

NCT04256759

COMPLETED NA

Impact of Predictive Modeling on Time to Palliative Care in an Outpatient Primary Care Population

NCT04604457

TERMINATED Phase 1

RBX7455 Before Surgery for the Treatment of Operable Breast Cancer

NCT04139993

COMPLETED

Stories for Change: Digital Storytelling Intervention for Diabetes Self-Management in the COVID-19 Pandemic

NCT04738032

COMPLETED NA

Effect of Medically-tailored Meal Delivery Service on Changes in Hemoglobin A1c (HbA1c) in Patients With Diabetes

NCT04523155

COMPLETED

Invasive Hemodynamic Response to Transcatheter Edge-to-Edge Mitral Valve Repair

NCT04200378

COMPLETED Phase 1

Interactive Care Plan for the Monitoring of Symptoms and Recovery in Patients With Stage 0-III Breast Cancer

NCT04693338

COMPLETED NA

Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting

NCT04352140

COMPLETED NA

Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve

NCT04352127

COMPLETED NA

Thumb vs Great Toe Recovery

NCT04312256

TERMINATED NA

A Study to Implement and Evaluate REFLECT Communication Curriculum for Oncology Based Medical Graduate Students

NCT04557696

TERMINATED

18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the Brain

NCT04462419

COMPLETED NA

Positive Suggestions Via MP3 Messages

NCT04437095

COMPLETED NA

Enhanced Kidney Follow-up for AKI Survivors in Care Transitions

NCT04505891

COMPLETED Phase 1

PET/CT Quantitative Assessment of Myocardial Blood Flow Changes in Oncologic Patients Receiving Checkpoint Inhibitor Therapy

NCT04538950

COMPLETED NA

Post-discharge Early Assessment With a Video-visit

NCT04547803

COMPLETED

Pathogenesis and Mechanisms of Mitral Annular Calcification

NCT04286009

COMPLETED Phase 2

8 Week Multi-site Study of MYDAYIS® for Bipolar Depression

NCT04235686

TERMINATED

Gastric Emptying Using Two Imaging Methods for Those Who Have Undergone POSE2 Weight Loss Procedure

NCT04502732

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.