Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 17 of 57

COMPLETED NA

Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

NCT05979883

COMPLETED NA

Stories for Change: Early Detection Can Save Lives

NCT05956353

COMPLETED NA

A Study of MUSE Device for Midlife Women

NCT05972486

COMPLETED

A Correlational Study: Breast Cancer-related Chest Wall Lymphedema, Quality of Life, and Shoulder Function

NCT06285747

COMPLETED NA

IV SafeLock Device Functionality in Emergency Department

NCT05695183

TERMINATED Phase 2

Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer

NCT04975516

COMPLETED Early Phase 1

Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis

NCT04899180

COMPLETED

Breast Cancer Survivors Who Experience Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)

NCT06106282

TERMINATED NA

A Study to Evaluate Safety and Effectiveness of G-POEM for Gastroparesis

NCT04869670

COMPLETED NA

Effect of Advanced Care at Home vs. Traditional Brick-and-Mortar Hospital Care in Acutely Ill Adults: A Pragmatic Clinical Trial

NCT05766956

TERMINATED Phase 2

PR3-AAV Resilient Remission or PRRR

NCT05376319

COMPLETED NA

A Study of Physical Activity in Cancer Survivors

NCT05988892

COMPLETED NA

A Study of Workflow-Integrated Artificial Intelligence for RPM Enrollment

NCT05744180

COMPLETED NA

Artificial Intelligence Enhanced ECG to Detect Cardiac Amyloidosis

NCT05557162

COMPLETED NA

A Study of Soundscapes for Patient Wellbeing

NCT05650073

COMPLETED NA

A Study of Overcoming Social Determinants of Health

NCT05773313

COMPLETED Phase 3

Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer

NCT05878405

COMPLETED

Qualitative Techniques to Define Meaningful Within-Patient Change in Symptoms of Advanced Cancer Patients

NCT06104657

TERMINATED NA

A Study of Non-invasive Measurement of Blood Glucose and Blood Pressure

NCT05904769

TERMINATED

A Study of Sleep Patterns to Determine Predictive Markers Due to Cardiovascular Disease in Elderly Patients

NCT05749263

COMPLETED NA

Evaluation of a Pain Management Intervention Preparatory to a Future Pragmatic Trial, ASCENT Study

NCT06063603

COMPLETED Phase 1

Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype

NCT05314374

TERMINATED NA

Needle-Based Confocal Laser Endomicroscopy for Diagnosis of Lung Cancer in Patients With Peripheral Pulmonary Nodules

NCT05556525

COMPLETED NA

Harnessing Health IT to Promote Equitable Care for Patients with Limited English Proficiency and Complex Care Needs

NCT05860777

COMPLETED NA

A Study of Spoken Language in Mania

NCT05956340

TERMINATED Phase 4

Paravertebral Block vs no Block in Open Pancreaticoduodenectomy

NCT05820997

TERMINATED

Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics

NCT05819827

COMPLETED NA

A Study to Detect Advanced Liver Disease Via AI-enabled Electrocardiogram

NCT05782283

COMPLETED

A Study of Endobiliary Radiofrequency Ablation in Malignant Biliary Obstructions

NCT05826639

COMPLETED

CARE: Cancer Risk Perception and Women of Color

NCT06036875

COMPLETED

Barriers to Cervical Cancer Screening

NCT06284447

TERMINATED Phase 4

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

NCT05552443

TERMINATED NA

Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration With Oscillating Expiratory Pressure

NCT05479604

COMPLETED Phase 2

A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension

NCT05564637

COMPLETED NA

Virtual World-Based Cardiac Rehabilitation

NCT05897710

COMPLETED NA

A Study of Internet Delivered Parent Child Interaction Therapy

NCT05725525

COMPLETED NA

A Study to Evaluate Animal-assisted Therapy in Stroke Rehabilitation

NCT05046574

TERMINATED

ALgorithms Adapted From Remote Monitoring

NCT05782140

TERMINATED Phase 2

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

NCT05005182

COMPLETED Phase 4

Steroids in Occipital Nerve Block for Treatment of Headache

NCT05732532

COMPLETED

Evaluation of Comprehensive Geriatric Assessment and Laboratory Biomarkers in Elderly Patients With Multiple Myeloma

NCT05918185

TERMINATED NA

A Study of Remote Electrical Neuromodulation for Acute Procedural Pain

NCT05730556

COMPLETED NA

The Feasibility and Acceptability of Utilizing Telehealth for Increasing Access to Bariatric Surgery

NCT05678179

COMPLETED NA

A Study of the GRIP Influenza and SARS-CoV-2 POC Assays

NCT05674370

COMPLETED NA

A Study of Plant-based Diet on Postprandial Sleepiness

NCT05706649

COMPLETED NA

Treatment of Symptomatic Bloating Using a Novel Hypnotherapy Protocol

NCT05572606

TERMINATED NA

"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures

NCT05523154

COMPLETED

A Study of Emergency Department AI Prediction Impact

NCT05683899

COMPLETED NA

Study of Music Therapy in Pain Rehabilitation Programs

NCT05676151

COMPLETED NA

Remote Mindfulness-Based Physical Activity Intervention for Postmenopausal Women

NCT05590507

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.