Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 18 of 57

COMPLETED NA

Vagal Nerve Stimulation for Post COVID Fatigue

NCT05445427

COMPLETED Phase 1

Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema

NCT05613946

COMPLETED NA

A Study of Baked Milk Tolerance to Treat Eosinophilic Esophagtis

NCT05606705

COMPLETED NA

Intubating Conditions of Neuromuscular Blockade

NCT05620108

COMPLETED NA

Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty Trial

NCT05559866

COMPLETED NA

A Study of a Multi-Modal Sensor Patch for Real-Time Physiological Monitoring and Inference

NCT05581290

COMPLETED NA

Patient Self-sampling of HPV to Screen for Cervical Cancer

NCT05600283

COMPLETED

An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas

NCT05560009

COMPLETED

Exploring Cultural Acceptability of Community Breast Cancer Risk Assessment Among Hispanic Women in Maricopa County

NCT06112795

COMPLETED NA

The Effects of Synaquell on Brain Function of Ice Hockey Players

NCT05498818

COMPLETED

Observational Study of Wearable Health Monitoring Device

NCT05368389

COMPLETED NA

Alaska Native Family-Based, Financial Incentives Intervention for Smoking Cessation

NCT05413265

TERMINATED

Evaluating the Accuracy of Microvessel Ultrasound Imaging for Detecting Extent of Disease in Patients With Angiosarcoma of the Skin

NCT05729425

COMPLETED NA

Wearable Devices to Monitor Seizures in Autoimmune Epilepsy

NCT05627661

COMPLETED

Sugammadex and Quantitative Monitoring in "Fast-Track Anesthesia" During Liver Transplantation

NCT05216991

TERMINATED Phase 1

E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma

NCT05388877

TERMINATED Phase 1

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

NCT05393713

COMPLETED NA

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

NCT05535257

COMPLETED

EEG Diagnostic for Repetitive Sub-concussive Head Impacts

NCT05562544

COMPLETED

A Study to Compare CSF Flow Metrics Across Platforms

NCT05221918

COMPLETED NA

Prevention of Hepatic Encephalopathy With Mobile Application Based Lactulose Titration

NCT05526404

TERMINATED NA

Cardiac Output and Recovery Time

NCT04619225

COMPLETED NA

A Study of Detergents in the Pathogenesis of Eosinophilic Esophagitis

NCT05482256

COMPLETED Phase 2

Cluster Headache Treatment With Rimegepant

NCT05264714

COMPLETED

Home-based Pulmonary Rehabilitation With Remote Monitoring in Pulmonary Arterial Hypertension

NCT05521113

COMPLETED NA

Vestibular Intervention Via Portable Electrical Stimulator (VIPES)

NCT04968197

COMPLETED NA

Effects of Energy Drinks on Sleep and Cardiovascular Health

NCT05503732

COMPLETED Phase 2

Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration

NCT05190744

COMPLETED

BIS Monitoring in Relation to Muscle Relaxant Administration

NCT05440058

COMPLETED

A Study of Home-based Pulmonary Rehabilitation and Health Coaching to Treat Bronchiectasis

NCT05553119

TERMINATED NA

Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue

NCT05407038

TERMINATED Phase 2

A Study to Assess the Role of Fenofibrate in Preventing Ischemic Cholangiopathy After Liver Transplantation

NCT05514119

COMPLETED

Predicting Burnout in Nurses

NCT05481138

COMPLETED NA

Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe

NCT05399082

COMPLETED Early Phase 1

IL-4 and Insulin Resistance for Treatment of Patients With Atopic Dermatitis

NCT05372003

COMPLETED NA

Pelvic CT with Agatston Calcium Score for Peyronie Disease

NCT05480683

COMPLETED NA

A Study to Evaluate 4DCT Controls

NCT04736537

COMPLETED NA

A Study of Music Therapy to Support Intrauterine Insemination

NCT05492331

COMPLETED NA

Feasibility of a Wireless Patch System (WPS) to Measure Gastrointestinal Motility and Gastric Emptying

NCT05555407

COMPLETED Phase 1

Butyrate Adjuvant Therapy for Type 1 Diabetes

NCT03999853

TERMINATED

Analysis of Letrozole in Patients With Operable Hormone Receptor Positive, HER2 Negative Breast Cancer

NCT05447910

COMPLETED NA

Normative Biomechanical Measures of Reaching in Able-Bodied Adults

NCT05328947

COMPLETED Early Phase 1

Safety and Feasibility of Kefir Administration in Critically Ill Adults

NCT05416814

COMPLETED

Patient Outcomes After Hepatic Artery Infusion Pump Placement

NCT05468593

COMPLETED

Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer

NCT05945290

COMPLETED

Treatments of Migraine with Triptans in Individuals with Elevated Cardiovascular Risk and in Pregnant Women

NCT05854992

COMPLETED NA

Slow Opioid Tapering Pilot Study of Patients Using Chronic Opioid Therapy

NCT05297396

COMPLETED

Effect of Acute Exercise on Exosome Associated Biomarkers

NCT05541133

COMPLETED NA

A Study to Validate Treadmill Parameters

NCT05333263

COMPLETED

Non-invasive Hemoglobin Monitoring in Outpatient Total Joint Arthroplasty

NCT05369325

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.