Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 16 of 57

COMPLETED

Feasibility of Saliva and Remote Monitoring of Active Cytomegalovirus (CMV) Infection and Symptoms During Ovarian Cancer Treatment

NCT06870539

COMPLETED Phase 4

Intravenous Methadone Versus Intrathecal Morphine for Analgesia Following Cesarean Delivery

NCT06826742

COMPLETED NA

Validation of Plant-Based Vegan Meal for Gastric Emptying Testing in 10 Healthy Subjects

NCT06991036

COMPLETED NA

Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

NCT06851546

COMPLETED NA

InBody Band 3 Fitness Tracker to Improve Health Outcomes and Quality of Life in Black Prostate Cancer Survivors

NCT06703996

COMPLETED NA

Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate

NCT06646406

COMPLETED NA

AI-SCREENDCM Decentralized Clinical Trial - Pilot Study

NCT06609174

COMPLETED Phase 4

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

NCT06625047

COMPLETED

The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

NCT06475768

COMPLETED NA

Sonography of the Nipple Areolar Complex

NCT06441188

COMPLETED NA

Subjective Sleep Quality of Patients With Chronic Insomnia

NCT06550388

COMPLETED

A Study of Cardiovascular Disease Awareness and Cardiovascular Health

NCT06523972

COMPLETED Phase 2

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for the Detection of Therapy Response in Patients With Metastatic Adenoid Cystic Carcinoma

NCT06521775

COMPLETED NA

Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis

NCT06316999

COMPLETED

A Case Report of NMDAR Encephalopathy

NCT06915103

COMPLETED NA

Increasing Access to Evidence-Based Care in Integrated Behavioral Health

NCT06347822

COMPLETED

Acute Gastrointestinal Bleeding Peripheral Pulse Volume Changes

NCT06441201

COMPLETED Phase 2

Comparison of Rimegepant and Placebo for Pain in IBS

NCT06221111

TERMINATED Phase 1

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

NCT06420349

COMPLETED NA

DermAI to Evaluate Human Factor of Testing

NCT06387472

COMPLETED Phase 4

Anti-Diabetic Medications to Fight PD and LBD

NCT06263673

COMPLETED

Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

NCT06401876

TERMINATED

Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women With Breast Cancer Receiving Chemotherapy

NCT06238986

COMPLETED NA

Evaluation of a Couple-Based Physical Activity Intervention

NCT06073951

COMPLETED Phase 2

Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT05730712

COMPLETED NA

Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)

NCT06268288

COMPLETED NA

Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity

NCT05343000

COMPLETED

Abdominal Aorta Palpation With Point of Care Ultrasound Imaging Measurements

NCT06211946

COMPLETED Phase 4

A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction

NCT05891613

COMPLETED Phase 1

Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

NCT06329492

COMPLETED Early Phase 1

A Study of Perturbation of Human Small Intestinal Colonic Permeability

NCT06033222

TERMINATED Phase 1

Durvalumab and Grid Therapy for Non-small Cell Lung Cancer in Progression During or After Treatment With PACIFIC Regimen

NCT05443971

COMPLETED

A Study of Metabolic Agents Following Brain Radiation

NCT06150547

COMPLETED NA

An Artificial Intelligence Algorithm for Identifying Gynecologic Cancer Patients in Need of Outpatient Palliative Care

NCT06182332

COMPLETED NA

A Study of Remote Asthma Management Using an Integrated Artificial Intelligence-assisted EHR Dashboard and Mobile Device Compared With Usual Asthma Care to Treat 6-17 Year Old Patients

NCT06062433

COMPLETED Phase 2

A Study of Ultra High Dose Diuretics to Treat Heart Failure

NCT06036914

COMPLETED

Urine-based Molecular Testing vs Cystoscopy for Surveillance of Nonmuscle Invasive Bladder Cancer (NMIBC)

NCT06126796

COMPLETED NA

A Study to Evaluate SimPull for Lateral Patient Transfer

NCT05856123

COMPLETED

Radioiodine Planar and a SPECT/CT Imaging With Iodine-123 for Evaluation of Follicular Thyroid Nodules Prior to Surgery

NCT05591092

COMPLETED Phase 2

A Study of Deucravacitinib to Treat LPP and FFA

NCT06091956

COMPLETED NA

Mechanical Power-Guided Lung Protective Ventilation (VentCoach) in Acute Hypoxemic and/or Hypercapnic Respiratory Failure

NCT07294768

COMPLETED NA

A Study of Hemp Hull WFI for IBS Diarrhea

NCT06028035

COMPLETED NA

Noninvasive Cochlear Stimulation System

NCT05112809

TERMINATED NA

SMART Program Impact on Quality of Life in Inflammatory Bowel Diseases

NCT06002074

TERMINATED Phase 4

A Study of Loco-Regional Liposomal Bupivacaine Injection

NCT05992896

COMPLETED

A Comparative Clinical Study to Determine the Optimal Initial Therapy for Multiple Myeloma

NCT06151717

COMPLETED NA

Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors

NCT06030427

COMPLETED NA

Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study

NCT05371509

COMPLETED

A Study of Effect of Megakaryocytes and Platelets in Breast Cancer

NCT06011824

COMPLETED NA

Acupressure for Reducing Anxiety in Patients Undergoing Chemotherapy

NCT06322615

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.