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NCT05523154 · ClinicalTrials.gov registry record · NA
"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures
A NA study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT05523154: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT05523154 is a NA study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05523154, a NA study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
This trial evaluates whether testing of bile with nanopore sequencing results in earlier detection of bacteriobilia (bacteria in bile) that may lead to surgical site infections in patients undergoing surgery for benign or malignant pancreatic tumors. Surgical site infections are a significant source of poor outcomes in patients undergoing surgery for pancreatic tumors. In most patients who develop this kind of infection, the bacteria identified as causing the infection is also frequently found to be in the bile at time of surgery. Usage of nanopore sequencing for detection of bacteria in the bile of patients undergoing surgery may allow doctors to prevent surgical site infections or treat them sooner or more effectively.
Primary Outcome
Assessed by incidence of surgical site infections (SSI), classified using American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) definitions. Diagnostics tests to evaluate for SSI included physical examination, laboratory testing, and imaging such as computed tomography (CT) and ultrasound (US). Patients with complicated hospital courses returned for clinical visit after approximately 2 weeks with cross sectional CT imaging and laboratory testing with further foll
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Laboratory Procedure
- DEVICE Nanopore Sequencing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2023-01-19 |
| Est. Completion | 2023-11-27 |
| Phase | NA |
Why NCT05523154 stopped before completion
NCT05523154 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Biospecimen Collection is the first listed.
NCT05523154 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05523154 about?
NCT05523154 is a clinical study titled ""Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures". This trial evaluates whether testing of bile with nanopore sequencing results in earlier detection of bacteriobilia (bacteria in bile) that may lead to surgical site infections in patients undergoing surgery for benign or malignant pancreatic tumors. Surgical site infections are a significant source...
What is the current status of trial NCT05523154?
This trial is currently terminated. It is a NA study. The enrollment target is 8 participants. The study started on 2023-01-19. Estimated completion is 2023-11-27.
What interventions are being tested in trial NCT05523154?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Laboratory Procedure (OTHER), Nanopore Sequencing (DEVICE).
Who is sponsoring clinical trial NCT05523154?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05523154's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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