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NCT05556525 · ClinicalTrials.gov registry record · NA
Needle-Based Confocal Laser Endomicroscopy for Diagnosis of Lung Cancer in Patients With Peripheral Pulmonary Nodules
A NA study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT05556525: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT05556525 is a NA study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05556525, a NA study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
This clinical trial compares the addition of needle-based confocal laser endomicroscopy (nCLE) and fluorescein to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA) with EBUS TBNA alone for the diagnosis of lung cancer in patients with peripheral pulmonary nodules. EBUS TBNA is a diagnostic procedure that can be used to sample lung tissue. nCLE is a novel high-resolution imaging technique that uses a laser light to create real-time microscopic images of tissues. It can be integrated into needles allowing real-time cancer detection during endoscopy. Fluorescein is an imaging agent that can be used to visualize tissue. Using nCLE and fluorescein in combination with EBUS TBNA may be more effective in diagnosing lung cancer than using EBUS TBNA alone.
Primary Outcome
Calculated as the proportion of patients for which first-pass transbronchial needle aspiration during bronchoscopic procedure yielded a definitive diagnosis out of the total number of patients that have received a diagnostic procedure.
Interventions
- PROCEDURE Ultrasound-Guided Transbronchial Needle Aspiration
- OTHER Fluorescein
- DEVICE Image-Guided Needle Confocal Laser Endomicroscopy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2023-05-12 |
| Est. Completion | 2024-10-25 |
| Phase | NA |
Why NCT05556525 stopped before completion
NCT05556525 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which Ultrasound-Guided Transbronchial Needle Aspiration is the first listed.
NCT05556525 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05556525 about?
NCT05556525 is a clinical study titled "Needle-Based Confocal Laser Endomicroscopy for Diagnosis of Lung Cancer in Patients With Peripheral Pulmonary Nodules". This clinical trial compares the addition of needle-based confocal laser endomicroscopy (nCLE) and fluorescein to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA) with EBUS TBNA alone for the diagnosis of lung cancer in patients with peripheral pulmonary nodules. EBUS TBN...
What is the current status of trial NCT05556525?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2023-05-12. Estimated completion is 2024-10-25.
What interventions are being tested in trial NCT05556525?
The interventions under investigation include: Ultrasound-Guided Transbronchial Needle Aspiration (PROCEDURE), Fluorescein (OTHER), Image-Guided Needle Confocal Laser Endomicroscopy (DEVICE).
Who is sponsoring clinical trial NCT05556525?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05556525's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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