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NCT07278570 · ClinicalTrials.gov registry record · NA
Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain
A NA study of Myofascial Pain and Myofascial Pain Syndrome - Lower Back, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 78
- Enrollment target
- 2
- Study locations
NCT07278570: Recruiting NA study of Myofascial Pain and Myofascial Pain Syndrome - Lower Back, sponsored by Mayo Clinic.
NCT07278570 is a NA study of Myofascial Pain and Myofascial Pain Syndrome - Lower Back that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 78 participants, above the 64-participant average among 8 other Myofascial Pain trials with a reported enrollment target (22% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07278570, a NA study of Myofascial Pain and Myofascial Pain Syndrome - Lower Back, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 78 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this research is to develop and test new Magnetic Resonance Imaging (MRI) methods that look at how muscles and tissues under the skin (myofascial tissues) move and respond to pressure. The investigators want to see how these tissues differ between healthy people and people with pain or injury, and how they change after hands-on treatment (Tuina therapy). The results will also be compared to a group that receives standard care without Tuina therapy. The main questions this study aims to answer are: 1. Can MR elastography (MRE) show changes in how the fascia and the layers between muscles move and stretch before and after manual therapy? 2. Do changes seen on MRE scans match changes in pain, function, and other symptoms reported by participants? 3. Can MRE measurements before treatment help predict which participants are most likely to improve with manual therapy? In this randomized controlled trial, participants with myofascial pain will be randomly assigned (randomized) to either the Tuina group or the Usual Care group following a home-based care program without manual therapy. All treatments are noninvasive, hands-on techniques commonly used in clinical practice to reduce tissue tightness and improve movement. Participants will be asked to undergo three MRI scans and to complete questionnaires and other standard clinical assessments about their pain, physical function, and quality of life.
Primary Outcome
The Pain, Enjoyment, and General Activity (PEG) score is a three-item questionnaire asking individuals to rate their Pain, Enjoyment of life, and General activity on a scale of 0 to 10 over the past week. The PEG score is the average of the three responses, ranging from 0 to 10, with higher scores indicating more severe pain or interference with life
Conditions Studied
Interventions
- OTHER Usual care
- OTHER Tuina treatment
Study Locations (2)
Minnesota
- Mayo Clinic in Rochester - Rochester
- Mayo Clinic Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 78 participants |
| Start Date | 2026-02-01 |
| Est. Completion | 2027-08-30 |
| Phase | NA |
What NCT07278570 shows while recruiting
NCT07278570 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 78 participants, a relatively small participant target, above the 64-participant average among 8 other Myofascial Pain trials with a reported enrollment target (22% higher).
The record links to 2 conditions, with Myofascial Pain appearing as the primary indexed condition, and to 2 interventions - of which Usual care is the first listed.
NCT07278570 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT07278570 about?
NCT07278570 is a clinical study titled "Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain". The purpose of this research is to develop and test new Magnetic Resonance Imaging (MRI) methods that look at how muscles and tissues under the skin (myofascial tissues) move and respond to pressure. The investigators want to see how these tissues differ between healthy people and people with pain o...
What is the current status of trial NCT07278570?
This trial is currently recruiting. It is a NA study. The enrollment target is 78 participants. The study started on 2026-02-01. Estimated completion is 2027-08-30.
What conditions does trial NCT07278570 study?
This clinical trial studies the following conditions: Myofascial Pain, Myofascial Pain Syndrome - Lower Back.
What interventions are being tested in trial NCT07278570?
The interventions under investigation include: Usual care (OTHER), Tuina treatment (OTHER).
Who is sponsoring clinical trial NCT07278570?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07278570 being conducted?
This trial has 2 study locations across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07278570's enrollment target sits among peer trials
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participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myofascial Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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