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NCT07487818 · ClinicalTrials.gov registry record · Phase 2
A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation
A Phase 2 study, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 150
- Enrollment target
NCT07487818: Recruiting Phase 2 study, sponsored by Mayo Clinic.
NCT07487818 is a Phase 2 study that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 150 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07487818, a Phase 2 study, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 150 participants
- Enrollment target
Study Summary
The purpose of this study is to provide preliminary evidence for the efficacy of 12 weeks of vagal nerve stimulation (VNS) and nicotine replacement therapy (NRT) for increasing smoking abstinence rates.
Primary Outcome
reporting smoking abstinence and having it be biochemically confirmed (CO reading of \< 8 ppm)
Interventions
- COMBINATION_PRODUCT Non-invasive vagus nerve stimulator plus nicotine replacement patches
- DRUG nicotine replacement patches
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-04-15 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 2 |
What NCT07487818 shows while recruiting
NCT07487818 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% higher).
The record links to 0 conditions, and to 2 interventions - of which Non-invasive vagus nerve stimulator plus nicotine replacement patches is the first listed.
NCT07487818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07487818 about?
NCT07487818 is a clinical study titled "A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation". The purpose of this study is to provide preliminary evidence for the efficacy of 12 weeks of vagal nerve stimulation (VNS) and nicotine replacement therapy (NRT) for increasing smoking abstinence rates.
What is the current status of trial NCT07487818?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2026-04-15. Estimated completion is 2027-05-31.
What interventions are being tested in trial NCT07487818?
The interventions under investigation include: Non-invasive vagus nerve stimulator plus nicotine replacement patches (COMBINATION_PRODUCT), nicotine replacement patches (DRUG).
Who is sponsoring clinical trial NCT07487818?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07487818's enrollment target sits among peer trials
150 455th of 2000 higher than 1,510 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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