Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 5 of 41
Lung Cancer Screening in High-risk Black Individuals
NCT05898594
A Single Session Parenting Intervention for Children on a Outpatient Therapy Waitlist
NCT06043271
Screening Trial for Pain Relief in Schwannomatosis (STARFISH)
NCT05684692
Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
NCT06003101
MOLAR: Mapping Oral Health and Local Area Resources
NCT05688982
Mapping Auricular Vagus Nerve Circuitry
NCT00200889
OCT Vibrography for Biomechanical Properties of Tissues
NCT05759780
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
NCT06429293
Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery
NCT05853627
Mechanisms of Anabolic Osteoporosis Therapy
NCT05688969
Optimal Stimulation Parameters to Disrupt Epileptiform Activity
NCT06141668
From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects
NCT05661903
AT1001 for the Treatment of Long COVID
NCT05747534
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
NCT05881239
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
NCT05866536
Tolerability of 532 nm Laser Treatment of Port Wine Stains
NCT05841628
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
NCT06538311
Clinical Validation of Samsung Smartwatch
NCT05767593
Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)
NCT06169540
Mechanisms Underlying Efficacy of Prolonged Exposure
NCT05788302
Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
NCT05799222
A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
NCT07219537
Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
NCT05524428
Mucolipidosis Type IV Natural History Study
NCT05782387
A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder
NCT05664516
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
NCT05570812
Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
NCT05668962
Double Blind, Placebo-controlled Trial to Establish Safety and Efficacy of Ritlecitinib in Celiac Disease Patients in Remission
NCT05636293
Health Opportunities and Promoters of Equitable Screening for Lung Cancer
NCT05784922
Training in Evidence-based Treatments in Psycho-Oncology
NCT05674357
Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy
NCT05646576
Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia
NCT05587127
Peripheral Neuroimmune Mechanisms of Hyperthermia
NCT05366270
Genetic Testing Decision Aid
NCT05470920
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
NCT05450432
Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes
NCT05420051
Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage
NCT05103566
Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery
NCT04912531
Collagen-targeted PET Imaging for Early Interstitial Lung Disease
NCT05417776
Positive Emotions Following Acute Cardiac Events
NCT05412862
Atezolizumab+Bevacizumab+SBRT in Unresectable HCC
NCT05096715
Cerebrospinal Fluid Biomarkers of Myotonic Dystrophy
NCT06075693
Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
NCT04940663
Abatacept in Immune Checkpoint Inhibitor Myocarditis
NCT05335928
Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
NCT05354232
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
NCT05237258
Intraoperative Tumor Margin Identification With ICG Dye Imaging
NCT04752137
Studying the Neuronal Basis of Human Social Cognition
NCT05324579
Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults
NCT05304286
Assess Fibrin in Brains With AD/ADRD
NCT05336695
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.