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NCT05304286 · ClinicalTrials.gov registry record · NA
Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults
A NA study of Chronic Post Surgical Pain, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 110
- Enrollment target
- 1
- Study location
NCT05304286: Recruiting NA study of Chronic Post Surgical Pain, sponsored by Massachusetts General Hospital.
NCT05304286 is a NA study of Chronic Post Surgical Pain that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 110 participants, below the 357-participant average among 4 other Chronic Post Surgical Pain trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05304286, a NA study of Chronic Post Surgical Pain, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
The current project will (1) enhance our understanding of the neurobiology of chronic post-surgical pain (CPSP); (2) provide a metric to follow patients with CPSP in the clinic; (3) provide a metric for those who will chronify; and (4) understand the age-related differences in CPSP. Ultimately, an improved comprehension of mechanisms linked to CPSP will provide finer tools for optimizing the selection of treatments for individual patients. Moreover, data that demonstrates the underlying pathobiological pain mechanism(s) active in CPSP, particularly those non-responsive to current therapies, may be used to validate novel strategies both pharmacological and non-pharmacological.
Primary Outcome
The 20-item CPAQ-revised has been designed to measure acceptance of pain. The acceptance of chronic pain is thought to reduce unsuccessful attempts to avoid or control pain and thus focus on engaging in valued activities and pursuing meaningful goals. The items on the CPAQ are rated on a 7-point scale from 0 (never true) to 6 (always true). To score the CPAQ, add the items for Activity engagement and Pain willingness to obtain a score for each factor. To obtain the total score, add the scores fo
Conditions Studied
Interventions
- BEHAVIORAL Acceptance and Commitment Therapy
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2022-04-07 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT05304286 shows while recruiting
NCT05304286 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 357-participant average among 4 other Chronic Post Surgical Pain trials with a reported enrollment target (69% lower).
The record links to 1 condition, with Chronic Post Surgical Pain appearing as the primary indexed condition, and to 1 intervention - of which Acceptance and Commitment Therapy is the first listed.
NCT05304286 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05304286 about?
NCT05304286 is a clinical study titled "Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults". The current project will (1) enhance our understanding of the neurobiology of chronic post-surgical pain (CPSP); (2) provide a metric to follow patients with CPSP in the clinic; (3) provide a metric for those who will chronify; and (4) understand the age-related differences in CPSP. Ultimately, an i...
What is the current status of trial NCT05304286?
This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2022-04-07. Estimated completion is 2026-06-30.
What conditions does trial NCT05304286 study?
This clinical trial studies the following conditions: Chronic Post Surgical Pain.
What interventions are being tested in trial NCT05304286?
The interventions under investigation include: Acceptance and Commitment Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05304286?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05304286 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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