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NCT06141668 · ClinicalTrials.gov registry record · NA

Optimal Stimulation Parameters to Disrupt Epileptiform Activity

A NA study of Refractory Epilepsy, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT06141668 is a NA study of Refractory Epilepsy that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 30 participants, below the 61-participant average among 4 other Refractory Epilepsy trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06141668, a NA study of Refractory Epilepsy, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Open-loop electrical stimulation has been found to reduce spike activity and seizures, but determining the optimal parameters to achieve these effects requires a brute force trial-and-error approach that relies on subjective physician discretion. We will compare the performance of stimulation parameters identified in rodent models to the recommended parameters for neuromodulation used in clinical practice.

Conditions Studied

Interventions

  • OTHER Neurostimulation

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2023-06-13
Est. Completion 2026-11-30
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT06141668

The ClinicalTrials.gov registry entry for NCT06141668 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 4 other Refractory Epilepsy trials with a reported enrollment target (51% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Refractory Epilepsy appearing as the primary indexed condition, and to 1 intervention - of which Neurostimulation is the first listed.

NCT06141668 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06141668 about?

NCT06141668 is a clinical study titled "Optimal Stimulation Parameters to Disrupt Epileptiform Activity". Open-loop electrical stimulation has been found to reduce spike activity and seizures, but determining the optimal parameters to achieve these effects requires a brute force trial-and-error approach that relies on subjective physician discretion. We will compare the performance of stimulation parame...

What is the current status of trial NCT06141668?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2023-06-13. Estimated completion is 2026-11-30.

What conditions does trial NCT06141668 study?

This clinical trial studies the following conditions: Refractory Epilepsy.

What interventions are being tested in trial NCT06141668?

The interventions under investigation include: Neurostimulation (OTHER).

Who is sponsoring clinical trial NCT06141668?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06141668 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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