Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 3 of 41
Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT
NCT06910956
Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL
NCT06849713
ASCENT Intervention for Brain Tumor Patients
NCT06099743
Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing
NCT06406114
Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease
NCT07613840
Preoperative Fasting vs. Not Fasting in Critically Ill Patients
NCT06751043
Improving Coronary Vascular Health in Women
NCT06843902
Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS
NCT06994494
TMS for Cognitive Decline in Aging and Preclinical AD
NCT06956300
G-CSF After Chemo-radiation in Patients With Glioblastoma
NCT06649851
Evaluating the Efficacy of RELiZORB in Managing Exocrine Pancreatic Insufficiency in Tube-fed Pancreatitis Patients
NCT06691893
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
NCT06533865
Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)
NCT06584942
Investigating Exercise in Myotonic Dystrophy Type 2 (DM2)
NCT06716931
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
NCT06201676
Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors
NCT05671133
Cannabis, Linked Emotions, and Adolescent Risk Study
NCT06576076
Fecal Microbiota Transplant for Autobrewery Syndrome
NCT06083142
A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences
NCT06929442
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
NCT06386588
Combined Anabolic Therapy
NCT06558188
Determining the Benefits of Exercise on Cardiovascular Risk in PTSD
NCT07260032
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
NCT05904132
A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors
NCT06541002
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
NCT06136546
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
NCT06375265
BMT-CARE: Psychosocial Intervention for Transplant Caregivers
NCT06472089
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
NCT06246929
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
NCT06192615
Efficacy of Synchronous, Virtual Cognitive Behavioral Therapy for Insomnia Across Phases of Cancer Survivorship
NCT06807086
Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM
NCT06561347
Family Members At INcreased-risk for Developing Inflammatory Bowel Disease
NCT06655415
Physiology of Human Brain Connectivity
NCT06246942
A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder
NCT06609902
Testing the mHealth App Intervention for Nondaily Smokers "SiS4"
NCT06678243
A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1
NCT06262113
Integrated Treatment for Enhancing Growth in Recovery During Adolescence
NCT06395467
Just-in-time Interventions for Reducing Short-term Suicide Risk
NCT05793541
REcovery From DEXmedetomidine-induced Unconsciousness
NCT06003127
Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU
NCT06568536
Psychoeducational Intervention for Patients With Hepatocellular Carcinoma
NCT06541990
Novel Digital Application for Patients With Acute Leukemia
NCT06472128
Use of a Colorectal Cancer Screening Decision Support Tool in Primary Care
NCT06625983
A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser
NCT06295471
The CurePSP Genetics Program
NCT06647641
Improving Health for Older Adults With Pain Through Engagement
NCT06119698
Behavioral Economics to Implement a Traffic Light Nutrition Ranking System: Study 2
NCT06298253
A Text- and Audio-based Intervention to Promote Physical Activity in Midlife
NCT06172933
Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder
NCT06274567
Cognitive Dysfunction in Chronic and Persistent Immune Thrombocytopenia
NCT06817395
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.