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NCT06751043 · ClinicalTrials.gov registry record · NA

Preoperative Fasting vs. Not Fasting in Critically Ill Patients

A NA study of Critical Illness and Fasting, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
1,072
Enrollment target
19
Study locations

NCT06751043 is a NA study of Critical Illness and Fasting that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 1,072 participants, below the 3,127-participant average among 91 other Critical Illness trials with a reported enrollment target (66% lower). The trial reports 19 study locations across 11 states.

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The verdict

NCT06751043, a NA study of Critical Illness and Fasting, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
1,072 participants
Enrollment target
19
Study locations

Study Summary

The goal of this clinical trial is to learn if fasting or not fasting before a procedure has an effect on recovery in those who are critically ill. The main questions it aims to answer for patients on a breathing machine who are receiving tube feeding are: * Does the risk of lung complications and death differ between those who are not fasting, which may have a higher chance of allowing tube feeding to enter the lungs, and fasting, which temporarily stops nutrition before a procedure? * Is there a difference in recovery times, hospital stays, infection rates, need for organ support, safety, and nutrition for those who either fast or do not fast before a procedure? * What is the relationship between nutrition and clinical outcomes? Researchers will compare not fasting and fasting to see if it has an effect on recovery. Participants will: * Be assigned by chance (like a coin toss) to one of two groups. One group (fasting group) will have their tube feeding stopped at least 8 hours before their procedure. The other group (not fasting group) will have their tube feeding stopped right before their procedure. * Be monitored via medical record for amount of protein and calories received, and any complications related to fasting/not fasting. * Receive a phone call from the study team about 3 months after they enter the study to see how they are doing and complete a questionnaire. '

Conditions Studied

Critical Illness Fasting Surgical Procedure, Unspecified Pulmonary Aspiration

Interventions

  • OTHER Fasting
  • OTHER Not fasting

Study Locations (19)

New York

  • Columbia University Irvine Medical Center - New York
  • Memorial Sloan Kettering Cancer Center - New York
  • University of Rochester Medical Center - Rochester
  • Montefiore Medical Center - The Bronx

Massachusetts

  • Mass General Hospital - Boston
  • Brigham & Women's Hospital - Boston
  • University of Massachusetts Memorial Medical Center - Worcester

California

  • Stanford Medical Center - Palo Alto
  • UCSF Medical Center Parnassus - San Francisco

Illinois

  • McGaw Medical Center of Northwestern - Chicago
  • Rush University Medical Center - Chicago

Texas

  • University of Texas Medical Branch - Galveston
  • UT Health Houston - Houston

Colorado

  • University of Colorado Medical Center - Aurora

Florida

  • University of Miami Hospital - Miami

Maryland

  • University of Maryland Medical Center - Baltimore

Trial Details

FieldValue
Enrollment Target 1,072 participants
Start Date 2025-04-28
Est. Completion 2028-05
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06751043

The ClinicalTrials.gov registry entry for NCT06751043 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 1,072 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,127-participant average among 91 other Critical Illness trials with a reported enrollment target (66% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Critical Illness appearing as the primary indexed condition, and to 2 interventions - of which Fasting is the first listed.

NCT06751043 reports 19 study locations spanning 11 distinct geographic areas - top geographies include New York, Massachusetts, California.

Frequently Asked Questions

What is clinical trial NCT06751043 about?

NCT06751043 is a clinical study titled "Preoperative Fasting vs. Not Fasting in Critically Ill Patients". The goal of this clinical trial is to learn if fasting or not fasting before a procedure has an effect on recovery in those who are critically ill. The main questions it aims to answer for patients on a breathing machine who are receiving tube feeding are: * Does the risk of lung complications and ...

What is the current status of trial NCT06751043?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,072 participants. The study started on 2025-04-28. Estimated completion is 2028-05.

What conditions does trial NCT06751043 study?

This clinical trial studies the following conditions: Critical Illness, Fasting, Surgical Procedure, Unspecified, Pulmonary Aspiration.

What interventions are being tested in trial NCT06751043?

The interventions under investigation include: Fasting (OTHER), Not fasting (OTHER).

Who is sponsoring clinical trial NCT06751043?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06751043 being conducted?

This trial has 19 study locations across California, Colorado, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.