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NCT06386588 · ClinicalTrials.gov registry record · NA
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
A NA study of Schizophrenia, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06386588 is a NA study of Schizophrenia that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 60 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06386588, a NA study of Schizophrenia, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at home for multiple nights. On some nights the headbands will play soft sounds at specific times during sleep. The investigators are interested in learning whether this timed auditory stimulation may be a strategy to improve the coordination of sleep rhythms across brain regions, improve network communication, and as a result, improve memory. The investigators will study 30 adults aged 18-45 with schizophrenia and 30 demographically matched healthy controls. Participants will first have a daytime MRI scan, during which they will complete a finger tapping motor sequence task (MST), followed by a week of sleep at home with a sleep headband. They will also do the MST at home on two of the nights. On the final day of the study, participants will return for a second MRI scan.
Conditions Studied
Interventions
- OTHER Closed loop auditory stimulation during sleep
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Charlestown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-02-05 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06386588
The ClinicalTrials.gov registry entry for NCT06386588 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (73% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Closed loop auditory stimulation during sleep is the first listed.
NCT06386588 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06386588 about?
NCT06386588 is a clinical study titled "The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia". In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at home for multiple nights. On some nights the headbands will play soft sounds at specific times during sleep. The investigat...
What is the current status of trial NCT06386588?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-02-05. Estimated completion is 2027-12-31.
What conditions does trial NCT06386588 study?
This clinical trial studies the following conditions: Schizophrenia.
What interventions are being tested in trial NCT06386588?
The interventions under investigation include: Closed loop auditory stimulation during sleep (OTHER).
Who is sponsoring clinical trial NCT06386588?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06386588 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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