Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 22 of 41

COMPLETED NA

A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making

NCT02698722

COMPLETED NA

Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness

NCT02845440

COMPLETED NA

Preventing Chronic Depression and PTSD in Stroke Patients Admitted to the Neuroscience Intensive Care Unit (NICU) and Their Family Caregivers

NCT02797509

COMPLETED NA

Resiliency Training for Patients With NF2 Via Videoconferencing With Skype

NCT02811718

TERMINATED NA

Physiological and Cognitive Biomarkers for Ketamine's Antidepressant Effects

NCT02669043

COMPLETED Early Phase 1

Reducing Side-effects of Autologous Skin Tissue Harvesting

NCT02234193

COMPLETED Phase 1

Fecal Microbiota Transplant for Improvement of Metabolism

NCT02530385

COMPLETED NA

Intraoperative Protective Ventilation and Postoperative Pulmonary Complications

NCT02671721

TERMINATED Phase 4

Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing

NCT02749292

COMPLETED NA

The Effect of Review of a Decision Aid Prior to the Appointment on Decisional Conflict Compared to Usual Care in the Treatment of Trapeziometacarpal (TMC) Arthritis

NCT03181724

COMPLETED Phase 2

A Study of Capmatinib (INC280) in NSCLC Patients With MET Exon 14 Alterations Who Have Received Prior MET Inhibitor

NCT02750215

COMPLETED NA

Evaluation of the Gastrointestinal Manifestation of Fabry's Disease

NCT02798458

COMPLETED NA

Palliative and Oncology Care Model in Breast Cancer

NCT02730858

COMPLETED Phase 1

Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy

NCT02471430

COMPLETED Early Phase 1

Fecal Microbiota Transplantation After HSCT

NCT02733744

COMPLETED Phase 1

IVIg to Treat BK Viremia in Kidney Transplant Recipients

NCT02659891

COMPLETED NA

PK/PD Pediatric ADHD Classroom Study

NCT02536105

COMPLETED NA

Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience

NCT03102710

TERMINATED

Validation of Thermal Imaging to Detect Pneumonia

NCT03261479

COMPLETED NA

Comparative Effectiveness of Decision Support Strategies for Joint Replacement Surgery

NCT02729831

COMPLETED NA

Shared Decision Making for Prescription Opioids After Cesarean Delivery

NCT02770612

COMPLETED

A Natural History of Late Onset Tay-Sachs Disease

NCT02851862

COMPLETED NA

Proactive Population Health Strategy to Offer Tobacco Dependence Treatment to Smokers

NCT03612895

COMPLETED NA

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

NCT02772302

COMPLETED Phase 4

Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon

NCT02516150

COMPLETED

a4b7 Integrin in Eosinophilic Esophagitis

NCT02546219

COMPLETED Phase 4

Ketamine for Depression: An MRI Study

NCT02544607

COMPLETED Phase 2

L-Threonic Acid Magnesium Salt (L-TAMS) in ADHD

NCT02558790

COMPLETED

Validation of Software-based Fusion of Ultrasound and MRI Images of the Prostate

NCT02882958

COMPLETED NA

Comparative Effectiveness of Metabolic and Bariatric Surgery With PROMs

NCT02749305

TERMINATED NA

The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas

NCT02701257

COMPLETED NA

Patient Navigation for Lung Screening at MGH Community Health Centers

NCT02705365

COMPLETED

Study of Pregnancy Regulation of Insulin and Glucose

NCT02763267

COMPLETED NA

Trial of Carbamylation in Renal Disease-Modulation With Amino Acid Therapy

NCT02472834

COMPLETED

Translational Investigation of Gestational Environment on Neurobehavioral Function in Children

NCT02715778

TERMINATED Phase 2

Impact of Infant Formula on Resolution of Cow's Milk Allergy

NCT02719405

TERMINATED Phase 2

Effects of Botox in Obstructed Defecation Syndrome

NCT02160288

COMPLETED NA

Neural Correlates of Successful Cognitive Aging

NCT02628548

COMPLETED

Noninvasive Physiologic Sensors to Assess Depression

NCT02568865

COMPLETED Phase 3

Reevaluation Of Systemic Early Neuromuscular Blockade

NCT02509078

COMPLETED NA

Comparative Effectiveness of Decision Aids for Stable Chest Discomfort

NCT02652208

COMPLETED Phase 2

Preventing Postpartum Depression With Intranasal Oxytocin

NCT02505984

COMPLETED Phase 1

MLN 9708 in Induction and Consolidation for Adults With AML >= 60 Years of Age

NCT02582359

COMPLETED NA

Supporting Patient Care With Electronic Resources in the United States

NCT02787538

COMPLETED NA

An Engagement Engine for Fitness Trackers

NCT02960386

COMPLETED NA

Pilot RCT Comparing Effectiveness of Two Decision Aids for Hip and Knee Osteoarthritis

NCT02625402

COMPLETED Phase 2

Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized Approach

NCT02553915

COMPLETED Phase 2

Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AML

NCT02560025

COMPLETED Phase 2

A Study of the Gut Barrier and Blood Vessel Inflammation in Individuals With and Without HIV

NCT02431325

COMPLETED NA

Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness

NCT02594696

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.