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NCT03102710 · ClinicalTrials.gov registry record · NA
Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 103
- Enrollment target
NCT03102710: Completed NA study, sponsored by Massachusetts General Hospital.
NCT03102710 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 103 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03102710, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 103 participants
- Enrollment target
Study Summary
The aim of this study is to use a brain stimulation tool called transcranial direct current stimulation (tDCS) to investigate the analgesic (reducing sensitivity to pain) effects of lidocaine cream and the hyperalgesic (increasing sensitivity to pain) effects of capsaicin cream using a neutral cream as a control. tDCS stimulation has been shown to temporarily influence the way the stimulated part of the brain functions. With this method, the involvement of specific parts of the brain can be investigated in the working of the brain as a whole.
Primary Outcome
We investigated the effects of cathodal (inhibition) and anodal (enhancement) tDCS on rDLPFC functional connectivity (FC) with the supplementary motor area (SMA) and anterior insula. Higher Fisher Z-scores represent greater resting-state functional connectivity.
Interventions
- DEVICE transcranial direct current stimulation (tDCS)
- OTHER Lidocaine cream
- OTHER Capsaicin cream
- OTHER Control cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 103 participants |
| Start Date | 2016-05 |
| Est. Completion | 2019-03 |
| Phase | NA |
What the finished NCT03102710 record still lists
NCT03102710 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 4 interventions - of which transcranial direct current stimulation (tDCS) is the first listed.
NCT03102710 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03102710 about?
NCT03102710 is a clinical study titled "Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience". The aim of this study is to use a brain stimulation tool called transcranial direct current stimulation (tDCS) to investigate the analgesic (reducing sensitivity to pain) effects of lidocaine cream and the hyperalgesic (increasing sensitivity to pain) effects of capsaicin cream using a neutral cream...
What is the current status of trial NCT03102710?
This trial is currently completed. It is a NA study. The enrollment target is 103 participants. The study started on 2016-05. Estimated completion is 2019-03.
What interventions are being tested in trial NCT03102710?
The interventions under investigation include: transcranial direct current stimulation (tDCS) (DEVICE), Lidocaine cream (OTHER), Capsaicin cream (OTHER), Control cream (OTHER).
Who is sponsoring clinical trial NCT03102710?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03102710's enrollment target sits among peer trials
103 837th of 2000 higher than 1,164 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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