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NCT02701257 · ClinicalTrials.gov registry record · NA

The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas

A NA study, sponsored by Massachusetts General Hospital.

Terminated
Registry status
NA
Development phase
20
Enrollment target

NCT02701257: Clinical Trial NA study, sponsored by Massachusetts General Hospital.

NCT02701257 is a NA study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02701257, a NA study, was terminated before completion, sponsored by Massachusetts General Hospital.

TERMINATED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

This study will compare two different models of a wearable bionic pancreas device (the iPhone-based bionic pancreas vs. the iLet bionic pancreas) in adult participant with type 1 diabetes. Both bionic pancreas devices measure glucose levels every five minutes and then give insulin and/or glucagon automatically to regulate the blood glucose (BG).

Primary Outcome

Average percent dose amounts calculated by the bionic pancreas control algorithm that are successfully delivered by the pump (aggregate of both insulin and glucagon doses) - primary outcome for iPhone-based BP using Lilly glucagon vs. iLet BP using Lilly glucagon

Interventions

  • DRUG Lilly glucagon
  • DEVICE iPhone bionic pancreas
  • DEVICE iLet bionic pancreas
  • DRUG Xeris Xerisol glucagon
  • DEVICE iLet infusion set

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2016-03
Est. Completion 2018-05
Phase NA
Massachusetts General Hospital

2,032 total trials

Why NCT02701257 stopped before completion

NCT02701257 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 5 interventions - of which Lilly glucagon is the first listed.

NCT02701257 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02701257 about?

NCT02701257 is a clinical study titled "The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas". This study will compare two different models of a wearable bionic pancreas device (the iPhone-based bionic pancreas vs. the iLet bionic pancreas) in adult participant with type 1 diabetes. Both bionic pancreas devices measure glucose levels every five minutes and then give insulin and/or glucagon au...

What is the current status of trial NCT02701257?

This trial is currently terminated. It is a NA study. The enrollment target is 20 participants. The study started on 2016-03. Estimated completion is 2018-05.

What interventions are being tested in trial NCT02701257?

The interventions under investigation include: Lilly glucagon (DRUG), iPhone bionic pancreas (DEVICE), iLet bionic pancreas (DEVICE), Xeris Xerisol glucagon (DRUG), iLet infusion set (DEVICE).

Who is sponsoring clinical trial NCT02701257?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02701257's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02701257, the US trial registry maintained by the National Library of Medicine. NCT02701257 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.