Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 21 of 41
Group Therapy for Depressed Dementia Caregivers
NCT03092050
Shift Work, Heredity, Insulin, and Food Timing Study
NCT02997319
Hyperthermic Yoga for Depressive Symptoms
NCT02607514
Preconception and Pregnancy Obesity Treatment and Prevention Among Women With a History of Depression
NCT03053323
Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.
NCT02836899
Automated Physician Notifications to Improve Guideline-Based Anticoagulation in Atrial Fibrillation
NCT02950285
Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant
NCT02945150
Viekira Pak or Mavyret Treatment for Patient With Chronic Kidney Disease and Hepatitis C
NCT02946034
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
NCT02676882
STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)
NCT02943590
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia
NCT02975869
Pilot Study of a Pharmacy Intervention for Older Adults With Cancer
NCT02871115
Effects of Eplerenone on Cardiovascular Disease in HIV (MIRACLE HIV Study)
NCT02740179
Multicenter Trial of the Effect of AAT on Islet Transplant Engraftment and Durability After Renal Transplant
NCT02464878
Boosting Emotions & Happiness in Outpatients Living With Diabetes: Phase I
NCT03001999
Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients
NCT02946580
Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study
NCT02860975
Strengthening of the First Dorsal Interosseous for Thumb Carpometacarpal Osteoarthritis
NCT03177577
Researching Emotions And Cardiac Health (REACH): Phase II
NCT02938052
Ustekinumab for the Treatment of Giant Cell Arteritis
NCT02955147
Development of a Resiliency Training Program for Parents of Children With Autism Spectrum Disorder
NCT02995408
Phenotypic Measurements and Their Relation to Disease Exacerbation in COPD Patients
NCT03300739
Support for Perinatal Adherence and Depression
NCT03069417
Augmentation of Treatment-Resistant Depression With An Analog of the Neuroactive Steroid Allopregnanolone
NCT02900092
Providing Preventive Periodontal Treatment to Hospitalized Patients With Diabetes
NCT02914743
Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)
NCT02959307
A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea
NCT03220529
A 60-seconds Personalized Mindfulness Video Exercise for Patients With Orthopedic Illness
NCT03212105
Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder: A Treatment Development and Pilot Study
NCT02963220
Repurposing Dexmedetomidine as an Orally Administered Sleep Therapeutic
NCT02818569
Transdisciplinary Intervention Integrating Geriatric And Palliative Care With Oncology Care For Older Adults With Cancer
NCT02868112
Development of a Resiliency Training Program for Parents of Children With Specific Learning Disabilities
NCT02772432
Image Guided Targeted Photoablation for the Treatment of Localized Hyperhidrosis
NCT04178161
Pilot Study of a Symptom Monitoring Intervention for Hospitalized Patients With Cancer
NCT02891993
Brain Mechanisms of Psychosocial Aspects of Acupuncture Therapy
NCT02908022
Promoting Employee Health Through The Worksite Food Environment
NCT02660086
Piloting Text Messages to Promote Positive Affect and Physical Activity
NCT04077229
Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection
NCT02810652
Post Bariatric Closed Loop Glucagon Trial
NCT02966275
Modified Comprehensive Behavioral Intervention for Tics (M_CBIT)
NCT02900144
TEACH: Technology Evaluation to Address Child Health
NCT02912000
AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
NCT02831257
Trauma Informed Intervention to Support Engagement in HIV Care Among MSM (THRIVE+)
NCT05822206
Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI
NCT02843230
Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan
NCT02985710
Neurobiological Underpinnings of Placebo Response in Depression
NCT02562430
HIV-to-HIV Transplant at MGH
NCT02750397
A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency
NCT02833610
Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects
NCT02874703
A Study Of Blinatumomab For The Treatment Of Relapsed Or Refractory Indolent Non-Hodgkin Lymphoma
NCT02811679
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.