Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 23 of 41
Imaging and BioFluid Biomarkers in Amyotrophic Lateral Sclerosis
NCT02559869
Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare, Inc.
NCT02601521
The Effects of Acute Weight Gain and Acute Calorie Deprivation on Marrow Adipose Tissue
NCT02482519
Online Yoga for Individuals With Mood Disorders
NCT02610725
A Pilot Randomized Controlled Trial of Financial Incentives, Text Messaging, and Usual Care for Homeless Smokers
NCT02565381
Thermal Imaging in Neonates: A Feasibility Study in Healthy Babies and Babies With Suspected TTN
NCT02570828
Helping Olfaction and Nutrition On Renal Replacement
NCT02479451
Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer
NCT02521051
Evaluation of the BOKS Before-school Physical Activity Program
NCT03190135
Pilot Study for Imaging of the Esophagus Using Tethered Capsule OCT Endomicroscopy With Distal Scanning
NCT02947997
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
NCT02551640
Use of 99mTc Tilmanocept for Imaging Arterial Inflammation
NCT02542371
Non Invasive Optical Imaging of WBC Count
NCT02512666
Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin Lymphoma
NCT02505269
The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance
NCT02509065
Effects of Mindfulness-based Cognitive Therapy on Brain Mechanisms in Depression
NCT02200341
A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas
NCT02448537
Outpatient Treatment of PE and DVT in the Emergency Department
NCT02532387
Effect of Harvoni on Proteinuria and eGFR in Hepatitis C Virus Associated Chronic Kidney Disease (CKD)
NCT02503735
A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma
NCT03405610
Tesamorelin Effects on Liver Fat and Histology in HIV
NCT02196831
Transdermal Estrogen in Older Premenopausal Women With Anorexia Nervosa
NCT02475265
Effect of High Doses of Radiation on Bone Structure and Metabolism
NCT02323295
Building Community Capacity for Disability Prevention for Minority Elders (Positive Minds - Strong Bodies)
NCT02317432
Vortioxetine for Menopausal Depression
NCT02234362
Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer
NCT02394548
Fostering Resilience to Psychosocial and HIV Risk in Indian MSM
NCT02556294
The Effect of Priming of Questionnaire Content on Grip Strength in Patients With Hand and Upper Extremity Illness
NCT02493127
A Multimodal Intervention to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors
NCT02492100
A Proof of Concept Study of Intravenous Sodium Nitroprusside in Adults With Symptomatic Schizophrenia
NCT02164981
Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive Therapies
NCT02410252
Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
NCT02355002
A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy
NCT02431572
Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation
NCT04467164
Changing Pediatric Office Systems Nationally to Address Parental Tobacco Use
NCT01882348
Community Servings: Food as Medicine for Diabetes
NCT02426138
Electronic-health Application To Measure Outcomes REmotely Clinical Trial
NCT02418546
Nasal Continuous Positive Airway Pressure and Airway Patency in Obese Patient
NCT03024723
Comparison of Stress Reduction Techniques
NCT02098018
A Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer
NCT02346526
Impact of the Relaxation Response Resiliency Program on Patients With Atrial Fibrillation
NCT02634697
Investigation of Female Reproductive Hormone Dynamics During Adolescence
NCT02486757
Examining Cognitive Mechanisms of Clinical Improvement Following Mindfulness Based Therapy for Depressed Individuals
NCT02457936
Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma
NCT02428855
A Proof of Concept Study of Electrical Discharge Produced Nitric Oxide for Inhalation
NCT02305550
Effects of Pitavastatin on Insulin Sensitivity and Liver Fat
NCT02290106
Improving Outcomes in Cancer Patients on Oral Anti-Cancer Medications Using a Multi-modal Mobile Health Intervention
NCT02375776
Evaluation of Vitamin K Supplementation for Calcific Uremic Arteriolopathy
NCT02278692
Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation
NCT02435641
Mood Patient Powered Research Network (MoodNetwork)
NCT02453438
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.