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NCT02831257 · ClinicalTrials.gov registry record · Phase 2

AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas

A Phase 2 study of Meningioma and Neurofibromatosis 2, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
18
Enrollment target
2
Study locations

NCT02831257: Completed Phase 2 study of Meningioma and Neurofibromatosis 2, sponsored by Massachusetts General Hospital.

NCT02831257 is a Phase 2 study of Meningioma and Neurofibromatosis 2 that has completed, run by Massachusetts General Hospital. The registered enrollment target is 18 participants, below the 99-participant average among 21 other Meningioma trials with a reported enrollment target (82% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02831257, a Phase 2 study of Meningioma and Neurofibromatosis 2, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
18 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical research study is to learn if the study drug AZD2014 can shrink growing or symptomatic meningiomas.

Primary Outcome

Number of Target Meningiomas with a Decrease in Tumor Volume of at least 20% Compared with Baseline

Interventions

  • DRUG AZD2014

Study Locations (2)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2016-08-31
Est. Completion 2020-10-01
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT02831257 record still lists

NCT02831257 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 99-participant average among 21 other Meningioma trials with a reported enrollment target (82% lower).

The record links to 2 conditions, with Meningioma appearing as the primary indexed condition, and to 1 intervention - of which AZD2014 is the first listed.

NCT02831257 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02831257 about?

NCT02831257 is a clinical study titled "AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas". The goal of this clinical research study is to learn if the study drug AZD2014 can shrink growing or symptomatic meningiomas.

What is the current status of trial NCT02831257?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2016-08-31. Estimated completion is 2020-10-01.

What conditions does trial NCT02831257 study?

This clinical trial studies the following conditions: Meningioma, Neurofibromatosis 2.

What interventions are being tested in trial NCT02831257?

The interventions under investigation include: AZD2014 (DRUG).

Who is sponsoring clinical trial NCT02831257?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02831257 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Meningioma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02831257's enrollment target sits among peer trials

18 21st of 21 higher than 1 of 21 other Meningioma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Meningioma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02831257, the US trial registry maintained by the National Library of Medicine. NCT02831257 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.