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NCT02562430 · ClinicalTrials.gov registry record · Phase 4

Neurobiological Underpinnings of Placebo Response in Depression

A Phase 4 study of Depression, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 4
Development phase
73
Enrollment target
1
Study location

NCT02562430: Completed Phase 4 study of Depression, sponsored by Massachusetts General Hospital.

NCT02562430 is a Phase 4 study of Depression that has completed, run by Massachusetts General Hospital. The registered enrollment target is 73 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02562430, a Phase 4 study of Depression, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 4
Development phase
73 participants
Enrollment target
1
Study location

Study Summary

In summary, the proposed research is novel with respect to design, technology, and its multi-level integration probing psychological and neurobiological constructs assumed to be crucially implicated in placebo response and has significant clinical and research implications for the future. Specifically, the future implications include: 1) identification of biomarkers and biosignatures of placebo responders, 2) new possibilities to understanding and manipulating the system, 3) possibly decreasing or eliminating a major confounder in clinical trials and drug development, and 4) refining treatments with novel drugs that decrease (in clinical trial) or increase (in clinical practice) the placebo response.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Welbutrin XL

Study Locations (1)

Massachusetts

  • Depression Clinical and Research Program at Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 73 participants
Start Date 2016-08
Est. Completion 2022-08
Phase Phase 4

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT02562430

The ClinicalTrials.gov registry entry for NCT02562430 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02562430 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02562430 about?

NCT02562430 is a clinical study titled "Neurobiological Underpinnings of Placebo Response in Depression". In summary, the proposed research is novel with respect to design, technology, and its multi-level integration probing psychological and neurobiological constructs assumed to be crucially implicated in placebo response and has significant clinical and research implications for the future. Specifical...

What is the current status of trial NCT02562430?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 73 participants. The study started on 2016-08. Estimated completion is 2022-08.

What conditions does trial NCT02562430 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT02562430?

The interventions under investigation include: Placebo (DRUG), Welbutrin XL (DRUG).

Who is sponsoring clinical trial NCT02562430?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02562430 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.