Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 20 of 41
Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)
NCT03168711
Preliminary Study 1 to Test the Effects of Ambulatory Voice Biofeedback
NCT03416829
Mitoxantrone, Etoposide, and Cytarabine (MEC) Plus Lenalidomide for Relapsed or Refractory Acute Myeloid Leukemia
NCT03118466
Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury
NCT03307070
A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)
NCT03149991
Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma
NCT03139916
Neuroimaging Biomarkers of Prognosis in Motor Functional Neurological Disorders
NCT03398070
Researching Emotions And Cardiac Health: Phase III
NCT03220204
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine
NCT02969876
Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy
NCT03740152
Efficacy of Glucagon In the Prevention of Hypoglycemia During Mild Exercise
NCT03217175
Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents
NCT03276221
Promoting Resiliency Among Lymphoma Survivors: The 3RP-Lymphoma
NCT03212261
Efficacy of Ostom-i Alert System at Decreasing Dehydration Related Complications
NCT02694757
The Set-Point Study for Type 2 Diabetes: Evaluating the Use of an Insulin Only Bionic Pancreas System in Type 2 Diabetes
NCT03552523
A Psychological-behavioral Intervention to Increase Activity in Type 2 Diabetes
NCT03164538
A Psychological-behavioral Intervention for Physical Activity in Type 2 Diabetes
NCT03150199
Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder
NCT03221738
Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOL
NCT03220100
Quantifying Skin Oxygenation Properties in Normal vs Sun Exposed Skin
NCT03311191
Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD
NCT02977299
The Effects of Oxytocin in Obese Adults
NCT03043053
Effect of Medical Marijuana on Neurocognition and Escalation of Use
NCT03224468
Beyond Confounders: Addressing Source of Measurement Variability and Error in Shear Wave Elastography
NCT03342560
Growth Hormone and Intrahepatic Lipid Content in Patients With Nonalcoholic Fatty Liver Disease
NCT02217345
Retention in HIV Care for Hispanic Immigrants
NCT03484117
Correlates of GERD Symptom Severity
NCT03020550
A Pilot Study of Cognitive-Behavioral Therapy for Rumination Disorder (CBT-RD)
NCT03062696
Evaluation of the Philips Lifeline CareSage Risk Assessment System
NCT03126565
Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
NCT03089125
Augmenting Growth Hormone to Ameliorate Nonalcoholic Fatty Liver Disease in Adolescents
NCT02726542
Brain Correlates of Self-Focused Processing
NCT02808702
Positive Psychology for Acute Coronary Syndrome Patients
NCT03122184
Vitamin D to Improve Outcomes by Leveraging Early Treatment
NCT03096314
Motivation-Audit-Positive Psychology Intervention Study
NCT03160755
Study of Regorafenib in Patients With Advanced Myeloid Malignancies
NCT03042689
Photobiomodulation in Autism Spectrum Disorder (ASD)
NCT03724552
Community Health Worker Care Transitions Study
NCT03085264
The Monitoring Study
NCT02969863
Light Therapy as Treatment for Fatigue in Multiple Sclerosis
NCT03060759
A Pilot Study Evaluating the Usability of the Oabi Mobile Application
NCT04534946
Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer Patients
NCT03019003
Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
NCT02961946
Randomized Study of a Hospice Video Educational Tool for Patients With Advanced Cancer and Their Caregivers
NCT03040102
Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain
NCT02959996
Acute Stress Response in Migraine Sufferers
NCT03099070
The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation
NCT03054506
Psychological Intervention for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation (HCT)
NCT03042715
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep
NCT02856594
Optical Frequency Domain Imaging for Non-melanoma Skin Cancers
NCT01662713
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.