Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 14 of 41
Pediatric Healthy Weight Clinic
NCT05020314
Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition
NCT04743960
AT1001 for the Treatment of COVID-19 Related MIS-C
NCT05022303
Toolkit for Optimal Recovery After Orthopedic Injury
NCT04973696
Text Messaging to Increase Activity in Midlife
NCT04849052
Intervention to Improve HIV Self-care Among People Who Inject Drugs
NCT05819411
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
NCT04809974
Feasibility of Outpatient Closed Loop Control With the iLet Bionic Pancreas in Cystic Fibrosis Related Diabetes
NCT03258853
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
NCT04827992
Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia
NCT04706091
Telehealth in an Ambulatory Oncology Phase I Clinical Trial Unit
NCT07069868
A Controlled Study of Solriamfetol for Attention Deficit Hyperactivity Disorder (ADHD) in Adults
NCT04839562
Buspirone Treatment of Anxiety in Williams Syndrome
NCT04807517
Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
NCT04136626
The Role of Fiber in the Prevention and Treatment of Fecal Incontinence
NCT04806386
Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy
NCT04566302
eCEASE to Support Treatment for Parental Tobacco Use
NCT04974736
Mind-body Resiliency Intervention for Fear of Cancer Recurrence
NCT04876599
Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members
NCT05183087
Gaining Optimism After Weight Loss Surgery (GOALS) I
NCT04867902
Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention
NCT04923880
FMT In High-Risk Acute GVHD After ALLO HCT
NCT04139577
The Effect of Opioid-Free Anesthesia in TMJ Surgery
NCT04724759
PREMIER: PREvention of Metabolic Illness Through prEcision nutRition
NCT04148482
Financial Incentives for Homeless Smokers: A Community-based RCT
NCT04445662
In Utero Exposure to SARS-CoV-2 (COVID-19) and Cardiovascular and Metabolic Endpoints in Early Life
NCT04921241
High Frequency Impulse Therapy for Neuropathic Pain in NMOSD
NCT04614454
Investigating the Impact of Professional Development Coaching for Faculty
NCT05036993
Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma
NCT04701918
Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas
NCT04730583
Laser Treatment for the Improvement of Scars and Scleroderma
NCT04567537
Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment
NCT04872738
QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir
NCT04515797
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
NCT04225624
MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT
NCT04799899
Covid-19 Vaccine Responsiveness in MM and Waldenstrom
NCT04830046
DEFINing the PrEvalence and Characteristics of Coronary Artery Disease Among Patients With TYPE 2 Myocardial Infarction Using CT-FFR
NCT04864119
Seguimos Avanzando - Latino Youth Coping With Discrimination
NCT04875208
The Patient Positioning for Perineal Protection Study
NCT04616170
Measuring Droplets in Children
NCT04518033
Noninvasive Biomarkers of Metabolic Liver Disease 1.1
NCT04828551
Disease Management Platform for Heart Failure (DMP-HF)
NCT04782973
Precision Medicine in Ischemic Stroke and Atrial Fibrillation
NCT04637087
Pembrolizumab And Lenvatinib In Leptomeningeal Metastases
NCT04729348
Lung Cancer Risk and Early Detection in Firefighters
NCT04614129
Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders
NCT04284267
A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.
NCT04507126
Hospital at Home at EOL in Heme Malignancies
NCT04690205
Refining the Shared Decision Making Process Survey in ADHD Medication Decisions
NCT05048186
Positive Minds Strong Bodies Implementation
NCT04545593
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.