Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 13 of 41
Augmented Infant Resuscitator (AIR): Transitioning a Novel Behavior Change Innovation to Drive Newborn Ventilation Skills Enhancement
NCT05349175
Living Well With Serious Illness "Wicokuje Sica Tuha Akisniya Wiconi": Wawokiya Health Advocate Intervention
NCT05208606
Weekly Family Food Packages: Food is Medicine
NCT05640414
Heart Rate Variability Biofeedback for Substance Use Disorder: A Randomized Clinical Trial
NCT05454657
Night Respite for Postpartum Mothers With SUD
NCT05746507
PEERS Plus mHealth Enhanced Peer Support
NCT05611996
Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas
NCT06120036
Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial
NCT05189106
Fluoxetine Treatment of Depression in Down Syndrome
NCT05458479
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
NCT06995560
Colonoscopy Screening: Setting Epic Follow-up Times
NCT05631873
Bridging the Gap From Postpartum to Primary Care
NCT05543265
Virtual Reality for Pain in Acute Orthopedic Injuries
NCT05552430
Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI
NCT05524402
Psychological Mobile App for Patients With AML
NCT05501171
Healthy Activities Improve Lives
NCT05670223
Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure
NCT05130008
A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery
NCT05780320
Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD
NCT05521074
Vulvovaginal Atrophy Questionnaire (VVAQ): Psychometric Validation of a Novel PROM
NCT04746456
The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease
NCT05364684
Culturally Aware AET Non-Initiation Intervention
NCT05465408
Gaining Optimism After Weight Loss Surgery (GOALS) II
NCT04868032
Enhancing Resilience in Senior Community Residents
NCT05438134
Varenicline for Nicotine Vaping Cessation in Adolescents
NCT05367492
Cognitive Behavior Therapy (CBT)-Based Group Intervention to Reduce Inflammation in Older People With HIV
NCT05434741
A Test of Efficacy and Foot Position Alteration in Patients Wearing Good Feet Arch Supports for the Treatment of Pain
NCT07103070
Therapist-Guided Smartphone-Delivered CBT for MDD
NCT05386329
Evaluation of a Resiliency Program for Fathers of Children and Youth With Special Health Care Needs
NCT05535348
Development of a Telehealth-delivered Peer Navigation and Coping Skills Intervention to Increase PrEP Use in Young Black MSM
NCT05769270
Managing Pain in Patients With Plantar Fasciitis - A Blinded Randomized Controlled Trial
NCT06116799
Well-being in IBS: Strengths and Happiness (WISH)
NCT05289089
Evaluating the Impact of an Equity Focused Dashboard and Clinical Support
NCT05278806
Mindfulness Oriented Recovery Enhancement in Hospitalized People With Opioid Use Disorder
NCT05066321
Neuroimaging Study of Dexmedetomidine-Induced Analgesia
NCT04656470
Pilot Study of a CF-specific CBT Intervention for Adolescents
NCT05271643
TMS for the Treatment of Primary Progressive Aphasia
NCT04188067
Weight Loss and Physical Activity Lifestyle Interventions In Post Liver And Kidney Transplants
NCT06249477
Evaluation of Transcranial Photobiomodulation in Autism Spectrum Disorder
NCT05363982
Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students
NCT05321563
MBG453 in Lower Risk MDS
NCT04823624
Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
NCT04759703
LiverPAL: A Pilot Study of Inpatient Palliative Care for Patients With Advanced Liver Disease
NCT04953143
Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at UVa
NCT05857488
Care Transition Intervention for Hospitalized Patients With Advanced Cancer
NCT05142345
Remote-delivered MBCT for SCAD Survivors
NCT04983680
Virtual Health Insurance Navigation Pilot Program for Colorectal Survivors
NCT05002608
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test
NCT04958109
Supportive Care Mobile Application for Patients With NSCLC
NCT04629300
Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery
NCT04291508
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.