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NCT04515797 · ClinicalTrials.gov registry record · Phase 4

QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir

A Phase 4 study, sponsored by Massachusetts General Hospital.

Terminated
Registry status
Phase 4
Development phase
2
Enrollment target

NCT04515797: Clinical Trial Phase 4 study, sponsored by Massachusetts General Hospital.

NCT04515797 is a Phase 4 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT04515797, a Phase 4 study, was terminated before completion, sponsored by Massachusetts General Hospital.

TERMINATED
Registry status
Phase 4
Development phase
2 participants
Enrollment target

Study Summary

This is a single center study characterizing the experience of administration of 4 weeks of pan-genotypic DAA therapy in kidney transplantation to prevent the transmission of hepatitis C virus infection from an HCV-positive donor kidney to an HCV-negative recipient.

Primary Outcome

Negative HCV RNA by blood testing at 12 weeks after the last dose of G/P

Interventions

  • DRUG Glecaprevir and Pibrentasvir

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2021-05-01
Est. Completion 2023-08-31
Phase Phase 4
Massachusetts General Hospital

2,032 total trials

Why NCT04515797 stopped before completion

NCT04515797 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which Glecaprevir and Pibrentasvir is the first listed.

NCT04515797 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04515797 about?

NCT04515797 is a clinical study titled "QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir". This is a single center study characterizing the experience of administration of 4 weeks of pan-genotypic DAA therapy in kidney transplantation to prevent the transmission of hepatitis C virus infection from an HCV-positive donor kidney to an HCV-negative recipient.

What is the current status of trial NCT04515797?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2021-05-01. Estimated completion is 2023-08-31.

What interventions are being tested in trial NCT04515797?

The interventions under investigation include: Glecaprevir and Pibrentasvir (DRUG).

Who is sponsoring clinical trial NCT04515797?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04515797's enrollment target sits among peer trials

2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04515797, the US trial registry maintained by the National Library of Medicine. NCT04515797 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.