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NCT04507126 · ClinicalTrials.gov registry record · Phase 2
A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.
A Phase 2 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
NCT04507126: Completed Phase 2 study, sponsored by Massachusetts General Hospital.
NCT04507126 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04507126, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
Study Summary
A pilot study of the effects of Bacillus Calmette-Guérin (BCG) immunization on cerebrospinal fluid and blood-based biomarkers in older adults.
Primary Outcome
Heat-killed BCG or Lipopolysaccharide (LPS) applied to peripheral blood mononuclear cells (PBMCs) from subjects at 0 and 90d after study start. Calculated as median fold change of cytokine levels in media at day 90 (pg/mL) compared to day 0 (pg/mL)
Interventions
- BIOLOGICAL Bacillus Calmette-Guerin (BCG)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-03-01 |
| Est. Completion | 2022-12-09 |
| Phase | Phase 2 |
What the finished NCT04507126 record still lists
NCT04507126 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 1 intervention - of which Bacillus Calmette-Guerin (BCG) is the first listed.
NCT04507126 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04507126 about?
NCT04507126 is a clinical study titled "A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.". A pilot study of the effects of Bacillus Calmette-Guérin (BCG) immunization on cerebrospinal fluid and blood-based biomarkers in older adults.
What is the current status of trial NCT04507126?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2021-03-01. Estimated completion is 2022-12-09.
What interventions are being tested in trial NCT04507126?
The interventions under investigation include: Bacillus Calmette-Guerin (BCG) (BIOLOGICAL).
Who is sponsoring clinical trial NCT04507126?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04507126's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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