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NCT04724759 · ClinicalTrials.gov registry record · Phase 2
The Effect of Opioid-Free Anesthesia in TMJ Surgery
A Phase 2 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT04724759: Completed Phase 2 study, sponsored by Massachusetts General Hospital.
NCT04724759 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04724759, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study aims is to evaluate the effect of opioid free total intravenous anesthesia on postoperative quality of recovery in patients undergoing oral and maxillofacial surgery (OMF) temporomandibular joint (TMJ) surgery.
Primary Outcome
Pain will be measured using the eleven point (0 to 10) numeric rating scale with higher values representing a worse outcome. Pain scores will be recorded every 15 minutes until discharge from the post-anesthesia care unit (PACU) and at 12 and 24 hours postoperatively. Clinically documented pain scores will be recorded. Our primary outcome will be the worst documented pain score while in the PACU. Additional pain score time points will be evaluated as secondary endpoints.
Interventions
- DRUG Dexmedetomidine / Ketamine / Lidocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-06-18 |
| Est. Completion | 2023-04-23 |
| Phase | Phase 2 |
What the finished NCT04724759 record still lists
NCT04724759 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 1 intervention - of which Dexmedetomidine / Ketamine / Lidocaine is the first listed.
NCT04724759 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04724759 about?
NCT04724759 is a clinical study titled "The Effect of Opioid-Free Anesthesia in TMJ Surgery". This study aims is to evaluate the effect of opioid free total intravenous anesthesia on postoperative quality of recovery in patients undergoing oral and maxillofacial surgery (OMF) temporomandibular joint (TMJ) surgery.
What is the current status of trial NCT04724759?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-06-18. Estimated completion is 2023-04-23.
What interventions are being tested in trial NCT04724759?
The interventions under investigation include: Dexmedetomidine / Ketamine / Lidocaine (DRUG).
Who is sponsoring clinical trial NCT04724759?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04724759's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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