Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 15 of 41
A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
NCT04672239
Usability of a Perioperative Medication-Related Clinical Decision Support Application
NCT04988737
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
NCT04548609
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
NCT01590862
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
NCT04569058
Care Transition Intervention for Patients With Cancer
NCT04640714
Wellbeing, Stress Reduction and Social Cognition
NCT04494737
Radiation Post-CAR T in Refractory Lymphoma
NCT04473937
Secondary Mentoring Program Evaluation
NCT04622163
Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation
NCT04230174
Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents
NCT04602494
Postoperative Neurocognitive Disorders
NCT04244162
PRevention Using EPA Against coloREctal Cancer
NCT04216251
Implementation of COVID-19 Testing Strategies in Community Health Centers
NCT04802187
Effect of Automated Real-time Feedback on Early Sepsis Care
NCT05625464
Development and Implementation of Electronic Decision Aids for Genetic Testing in Inherited Cancer Syndromes
NCT04704193
Lung Cancer Screening Navigation for Homeless People
NCT04308226
Enhancing Acupuncture Treatment Effect Through Non-invasive Neuromodulation
NCT03716830
Effects of Respiratory-Gated Transcutaneous Vagal Nerve Stimulation in Major Depression (Phase 1)
NCT04607226
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
NCT04726371
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download
NCT05346380
Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled Trial
NCT04620486
Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
NCT04015596
Survivorship Sleep Program
NCT04566068
Evaluating the Shared Decision Making Process Scale in Cancer Screening Decisions
NCT04601272
A Text Message Intervention to Promote Health Behaviors in Cardiac Risk Conditions
NCT04382521
Light Therapy for PD - Dose Selection
NCT04291014
The ENCHANTMENT HIV Study
NCT04153136
Engaging Patients in Colon Cancer Screening Decisions During COVID-19
NCT04548531
My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based Practices
NCT04537728
Modulation Effects of Baduanjin Exercise on Subjective Cognitive Decline
NCT04009382
Developing a Health Insurance Navigation Program for Survivors of Childhood Cancer
NCT04520061
mFOCUS (Multilevel FOllow-up of Cancer Screening)
NCT03979495
Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery
NCT04087096
First Heroes: Engaging Fathers in the First 1000 Days
NCT04477577
Immune Checkpoint Inhibitors and Atherosclerotic Plaque Volume
NCT04430712
Tc99m-MAA Bronchial Artery Injection During Bronchial Embolization for Pulmonary Mass Induced Hemoptysis for Dosimetry Planning
NCT04105283
Prolonged Nightly Fasting in Breast Cancer Survivors
NCT04330339
Niraparib + Dostarlimab + RT in Pancreatic Cancer
NCT04409002
Effect of Tai Chi as Treatment for IBS-C
NCT04132804
Vaccine Responsiveness in Patients With Chronic Lymphocytic Leukemia
NCT05007860
Understanding Daily Changes in BDD Risk Using Smartphones
NCT04254575
Prognostication of Recovery in Early Disorders of Consciousness After COVID-19
NCT04476589
Patients' Preferences About Rescheduling Colonoscopies Delayed Due to COVID-19: Cross Sectional Study
NCT04432870
MGH Trauma-related Nightmares SDI Study
NCT05195684
Home Hospital for Lymphoma
NCT04423848
PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT
NCT04158804
Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD
NCT04458103
Examining Validity and Reliability of the Shared Decision Making Process Survey in Adults With Depression
NCT04343534
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms
NCT04231097
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.