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NCT04827992 · ClinicalTrials.gov registry record · NA
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 87
- Enrollment target
NCT04827992: Completed NA study, sponsored by Massachusetts General Hospital.
NCT04827992 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 87 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04827992, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 87 participants
- Enrollment target
Study Summary
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain intensity and interference when added to a 24-week behavioral intervention (POTS).
Primary Outcome
Median opioid dose verified by the Prescription Monitoring Program, in morphine milligram equivalents (MME) per day, over monthly interval preceding study visit.
Interventions
- DRUG Cannabis
- BEHAVIORAL Prescription Opioid Taper Support (POTS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2021-08-23 |
| Est. Completion | 2025-10-31 |
| Phase | NA |
What the finished NCT04827992 record still lists
NCT04827992 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Cannabis is the first listed.
NCT04827992 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04827992 about?
NCT04827992 is a clinical study titled "Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain". This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain intensity and interference when added to a 24-week behavioral intervention...
What is the current status of trial NCT04827992?
This trial is currently completed. It is a NA study. The enrollment target is 87 participants. The study started on 2021-08-23. Estimated completion is 2025-10-31.
What interventions are being tested in trial NCT04827992?
The interventions under investigation include: Cannabis (DRUG), Prescription Opioid Taper Support (POTS) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04827992?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04827992's enrollment target sits among peer trials
87 974th of 2000 higher than 1,025 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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