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NCT02040558 · ClinicalTrials.gov registry record · Phase 1
Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors
A Phase 1 study, sponsored by Mallinckrodt.
- Terminated
- Registry status
- Phase 1
- Development phase
- 44
- Enrollment target
NCT02040558: Clinical Trial Phase 1 study, sponsored by Mallinckrodt.
NCT02040558 is a Phase 1 study that was terminated before completion, run by Mallinckrodt. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02040558, a Phase 1 study, was terminated before completion, sponsored by Mallinckrodt.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
This is a multicenter, open-label, dose escalation study of MNK-010 in subjects with advanced solid malignancies who have failed conventional therapy. The safety, tolerability, pharmacokinetic (PK) profile, and preliminary antitumor activity of ascending doses of MNK-010 will be evaluated in subjects with advanced solid tumors.
Primary Outcome
MTD of MNK-010
Interventions
- DRUG MNK-010
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2013-07 |
| Est. Completion | 2016-07 |
| Phase | Phase 1 |
Why NCT02040558 stopped before completion
NCT02040558 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).
The record links to 0 conditions, and to 1 intervention - of which MNK-010 is the first listed.
NCT02040558 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02040558 about?
NCT02040558 is a clinical study titled "Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors". This is a multicenter, open-label, dose escalation study of MNK-010 in subjects with advanced solid malignancies who have failed conventional therapy. The safety, tolerability, pharmacokinetic (PK) profile, and preliminary antitumor activity of ascending doses of MNK-010 will be evaluated in subject...
What is the current status of trial NCT02040558?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2013-07. Estimated completion is 2016-07.
What interventions are being tested in trial NCT02040558?
The interventions under investigation include: MNK-010 (DRUG).
Who is sponsoring clinical trial NCT02040558?
This trial is sponsored by Mallinckrodt, which has 69 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02040558's enrollment target sits among peer trials
44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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