Kowa Research Institute

44 total trials 39 completed

Kowa Research Institute sponsors 44 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 39 completed. 15 of these trials are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 2 trials.

Trial Pipeline

44 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

NCT06247735

ACTIVE NOT RECRUITING Phase 2

Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis

NCT05327127

COMPLETED Phase 1

A Study to Evaluate the Pharmacokinetics and Safety of K-808 (Pemafibrate) in Subjects With Primary Biliary Cholangitis With Compensated Cirrhosis and Without Cirrhosis.

NCT06525311

COMPLETED Phase 3

A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

NCT05826353

COMPLETED Phase 3

A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

NCT05795699

COMPLETED Phase 1

Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER and CSG452

NCT05722262

COMPLETED Phase 3

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

NCT05528172

COMPLETED Phase 3

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

NCT05403827

COMPLETED Phase 1

Study to Assess the Food Effect of K-877 in Healthy Adult Volunteers

NCT04742218

TERMINATED Phase 2

A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity

NCT04484428

COMPLETED Phase 2

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

NCT04250207

COMPLETED Phase 2

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

NCT04447820

COMPLETED Phase 1

Pharmacokinetic Drug-Drug Interaction Study Between K-877 and CSG452 in Healthy Adult Volunteers

NCT04237597

COMPLETED Phase 2

A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease

NCT04084483

COMPLETED Phase 1

Compare the Pharmacokinetic of K-877 Controlled Release (CR) and Immediate Release (IR) Tablets in Healthy Adults.

NCT03702673

COMPLETED Phase 1

Evaluate the Safety, Tolerability, & Pharmacokinetics of K-285 Compared With Indomethacin Capsule in Healthy Adults

NCT03712241

COMPLETED NA

Study to Compare Kowa OCT Bi-μ and the Optovue iVue 100

NCT03505567

TERMINATED Phase 3

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

NCT03071692

COMPLETED Phase 3

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

NCT03001817

COMPLETED Phase 3

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

NCT03011450

COMPLETED Phase 1

Drug-Drug Interaction Study to Assess the Effects of Multi Dose Clopidogrel on the Pharmacokinetics of Single-Dose K-877 in Healthy Adult Volunteers

NCT02922465

COMPLETED Phase 1

Drug-Drug Interaction Study to Assess the Effects of Multiple-Dose Administration of K-877 on the Pharmacodynamics and the Pharmacokinetics of Multiple-Dose Administration of Warfarin in Healthy Adult Volunteers

NCT02719431

COMPLETED Phase 1

A Comparison Study to Evaluate the Pharmacokinetics and Safety of NK-104-CR in Healthy Adult Volunteers

NCT02634034

COMPLETED Phase 1

Drug-Drug Interaction Study in Healthy Adult Volunteers

NCT02275962

COMPLETED Phase 1

Drug-Drug Interaction Study in Health Adult Volunteers

NCT02273986

COMPLETED Phase 1

Evaluation of Absorption, Metabolism, and Excretion and Estimation of the Absolute Bioavailability of K-312

NCT02676830

COMPLETED Phase 1

Drug-Drug Interaction Study in Healthy Adult Volunteers

NCT02275975

COMPLETED Phase 1

Drug-Drug Interaction Study in Healthy Adult Volunteers

NCT02275988

COMPLETED Phase 1

Drug-Drug Interaction Study in Healthy Adult Volunteers

NCT02276001

COMPLETED Phase 1

Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects

NCT02676596

TERMINATED Phase 3

An Efficacy and Safety Study for the Treatment of Mild to Moderate Acute Pain Associated With Ankle Strain or Sprain.

NCT02089425

COMPLETED Phase 1

A Thorough Corrected QT Interval Trial

NCT02073084

COMPLETED Phase 1

Study Comparing the Pharmacokinetics, Pharmacodynamics, and Safety of K-312 in Healthy Adult Volunteers

NCT01952548

COMPLETED Phase 4

Drug-Drug Interaction of Cardizem LA (Diltiazem Hydrochloride) on Pitavastatin

NCT01422382

COMPLETED Phase 4

Drug-Drug Interaction of Darunavir/Ritonavir on Pitavastatin

NCT01422369

COMPLETED Phase 4

A 12-Week Study Comparing Pitavastatin 4 mg vs. Pravastatin 40 mg in HIV-Infected Subjects

NCT01301066

COMPLETED Phase 4

Prevail-Us: A Study Of Pitavastatin 4 mg Vs. Pravastatin 40 mg In Patients With Primary Hyperlipidemia Or Mixed Dyslipidemia

NCT01256476

COMPLETED Phase 4

Drug-Drug Interaction Study to Assess the Effects of Steady State Pitavastatin 4 mg or Rosuvastatin 40 mg on Steady-State Warfarin in Healthy Adult Volunteers

NCT01178853

COMPLETED Phase 2

A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy

NCT01169090

COMPLETED Phase 1

A Multicenter, Open Label, Single Dose Study to Evaluate the Effect of Renal Insufficiency on the Pharmacokinetics of SK 0403

NCT01131091

COMPLETED Phase 4

Drug-Drug Interaction of Lopinavir/Ritonavir on Pitavastatin

NCT01057433

COMPLETED Phase 4

Safety, Tolerability, and Pharmacokinetic of Single Dose of Pitavastatin 4 mg in Severe Renal Patients Versus Healthy Adult Volunteers

NCT01043094

COMPLETED Phase 2

A Trial of the Safety and Efficacy of K-604 for the Treatment of Atherosclerosis

NCT00851500

COMPLETED Phase 2

Safety and Efficacy of K-134 for the Treatment of Intermittent Claudication

NCT00783081

Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 9
Phase 3 8
Phase 4 7

What the Pipeline for Kowa Research Institute Shows

According to the ClinicalTrials.gov registry, Kowa Research Institute is linked to 44 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 39 are already marked complete, representing roughly 89% of the total.

The phase mix for Kowa Research Institute reports 15 late-stage studies (Phase 3 and Phase 4 combined) and 28 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Kowa Research Institute is Healthy with 2 linked trials, and 7 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.