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NCT05327127 · ClinicalTrials.gov registry record · Phase 2

Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis

A Phase 2 study of NASH, sponsored by Kowa Research Institute.

Active
Registry status
Phase 2
Development phase
228
Enrollment target
20
Study locations

NCT05327127 is a Phase 2 study of NASH that is active but no longer recruiting, run by Kowa Research Institute. The registered enrollment target is 228 participants, roughly in line with the 229-participant average among 10 other NASH trials with a reported enrollment target. The trial reports 20 study locations across 11 states.

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The verdict

NCT05327127, a Phase 2 study of NASH, is active but no longer recruiting, sponsored by Kowa Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
228 participants
Enrollment target
20
Study locations

Study Summary

A study to investigate the use of combination therapy with two investigational products for the treatment of adult patients with Nonalcoholic steatohepatitis (NASH).

Conditions Studied

NASH

Interventions

  • DRUG Placebo
  • DRUG K-877-ER
  • DRUG CSG452

Study Locations (20)

Florida

  • Nature Coast Clinical Research, LLC - Inverness
  • ENCORE Borland Groover Clinical Research - Jacksonville
  • Miami Clinical Research - Miami
  • Ocala GI Research - Ocala
  • Sensible Healthcare Clinical Research, LLC - Ocoee

California

  • Clinical Trials Research - Lincoln
  • United Clinical Research Institute - Los Alamitos
  • Velocity Clinical Research - Los Angeles
  • Alliance Clinical Research - Poway

Arizona

  • Adobe Clinical Research, LLC - Tucson
  • Arizona Liver Health - Tucson

Georgia

  • Centricity Research - Columbus
  • Gastrointestinal Specialists of Georgia, PC - Marietta

Arkansas

  • Arcare Center for Clinical Research - Little Rock

Iowa

  • Iowa Digestive Disease Center - Clive

Louisiana

  • Tandem Clinical Research, LLC - Marrero

Maryland

  • Mid-Atlantic GI Research, LLC - Greenbelt

Trial Details

FieldValue
Enrollment Target 228 participants
Start Date 2022-11-14
Est. Completion 2026-03
Phase Phase 2

Sponsor

Kowa Research Institute

44 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05327127

The ClinicalTrials.gov registry entry for NCT05327127 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 228 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 229-participant average among 10 other NASH trials with a reported enrollment target. The listed sponsor is Kowa Research Institute, which has 44 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with NASH appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT05327127 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Florida, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT05327127 about?

NCT05327127 is a clinical study titled "Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis". A study to investigate the use of combination therapy with two investigational products for the treatment of adult patients with Nonalcoholic steatohepatitis (NASH).

What is the current status of trial NCT05327127?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 228 participants. The study started on 2022-11-14. Estimated completion is 2026-03.

What conditions does trial NCT05327127 study?

This clinical trial studies the following conditions: NASH.

What interventions are being tested in trial NCT05327127?

The interventions under investigation include: Placebo (DRUG), K-877-ER (DRUG), CSG452 (DRUG).

Who is sponsoring clinical trial NCT05327127?

This trial is sponsored by Kowa Research Institute, which has 44 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05327127 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.