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ClinicalTrials.gov 4 recruiting now official registry

NASH clinical trials

4 of 11 indexed NASH trials are currently recruiting.

11 US clinical trials · 4 currently recruiting

NASH is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Neuraly, running 1 of these trials.

The research picture

NASH has 11 registered US clinical trials, 4 of them open to new participants right now, about 36% of the total.

4
recruiting participants now
36%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
1
top sponsor: Neuraly
Phase 24Phase 31

Active & Recent Trials

11 total, page 1 of 1

RECRUITING 400 participants

Evaluation of Non-Invasive Tests for Metabolic Liver Disease

Foundation for the National Institutes of Health

NCT07122700

RECRUITING 150 participants

Androgens and NAFLD Longitudinal Cohort Study

University of California, San Francisco

NCT06124261

RECRUITING Phase 2 144 participants

Digoxin In NASH (CODIN)

Yale University

NCT06588699

RECRUITING NA 20 participants

Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis

Milton S. Hershey Medical Center

NCT06195943

ACTIVE NOT RECRUITING Phase 3 700 participants

A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)

Madrigal Pharmaceuticals

NCT05500222

ACTIVE NOT RECRUITING 450 participants

LITMUS Imaging Study

University of Oxford

NCT05479721

ACTIVE NOT RECRUITING Phase 2 228 participants

Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis

Kowa Research Institute

NCT05327127

ACTIVE NOT RECRUITING Phase 2 67 participants

A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH

Neuraly

NCT06410924

ACTIVE NOT RECRUITING NA 24 participants

An Imaging-based Quantitative Biomarker Assay for NAFLD in Children

University of Wisconsin, Madison

NCT06354491

COMPLETED 233 participants

Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Liver Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT05669677

COMPLETED Phase 2 102 participants

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD)

Aligos Therapeutics

NCT06342947

Phase Distribution

PhaseTrial count
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the NASH Trial Landscape

11 indexed NASH studies · 4 recruiting (36%).

Phase mix: 1 late (III/IV) vs 4 early (I/II).

Top sponsor: Neuraly (1 trial), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for NASH?

PlainTrial tracks 11 US clinical trials for NASH, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for NASH?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.