Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Fuchs Endothelial Corneal Dystrophy: early-phase trial registry
2 of 4 indexed Fuchs Endothelial Corneal Dystrophy trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #4,115 of 28,707 conditions by registered trial count.
4 US clinical trials · 2 currently recruiting · #4,115 of 28,707 conditions by registered trial count
Fuchs Endothelial Corneal Dystrophy: 4 US clinical trials tracked, 2 recruiting.
Fuchs Endothelial Corneal Dystrophy is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Trefoil Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition fuchs-endothelial-corneal-dystrophy
OPEN 2 | RECR 50% | LATE 1 | EARLY 3 | RANK #4115 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Fuchs Endothelial Corneal Dystrophy lists 2 open slots (50% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Fuchs Endothelial Corneal Dystrophy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Fuchs Endothelial Corneal Dystrophy is recruiting above its size-band peers.
2 of 4 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
4 total, page 1 of 1
Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary
NCT04440280
DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy
Design Therapeutics
NCT07024693
A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)
Kowa Research Institute
NCT05795699
A Phase 1/ Phase 2 Study of TTHX1114(NM141)
Trefoil Therapeutics
NCT04520321
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Fuchs Endothelial Corneal Dystrophy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Fuchs Endothelial Corneal Dystrophy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Fuchs Endothelial Corneal Dystrophy page
4 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Fuchs Endothelial Corneal Dystrophy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Trefoil Therapeutics sponsors the most Fuchs Endothelial Corneal Dystrophy trials on record, review their full trial history before evaluating a specific study. See Trefoil Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Fuchs Endothelial Corneal Dystrophy condition card totals 4 registered trials; most-linked intervention Vehicle (placebo); top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.