Aclaris Therapeutics

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Aclaris Therapeutics sits in the top decile of US sponsors by registered trial count (#500 of 15,742 sponsors by registered trial count).

33 total trials 1 currently recruiting 28 completed early-phase tilt top decile by trial count

Aclaris Therapeutics: 33 sponsored US clinical trials, 1 recruiting.

Aclaris Therapeutics sponsors 33 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 28 completed. 8 of these trials are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Common Wart, with 2 trials.

Top-decile sponsor footprint

Aclaris Therapeutics ranks in the top decile of sponsors by registered trial count (#500 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 58/100

28 of 32 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

33 total, page 1 of 1

RECRUITING Phase 2

ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis

NCT07011706

COMPLETED Phase 2

Study of ATI-2138 in Adult Participants With Moderate to Severe Atopic Dermatitis

NCT06585202

TERMINATED Phase 2

Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis

NCT05511519

COMPLETED Phase 2

Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Dermatitis

NCT05432596

COMPLETED Phase 2

ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)

NCT05279417

COMPLETED Phase 2

ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)

NCT05216224

TERMINATED Phase 2

Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS)

NCT04524858

COMPLETED Phase 2

Study of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis

NCT04598269

COMPLETED Phase 2

Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA

NCT04247815

COMPLETED Phase 3

Safety Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03812510

TERMINATED Phase 2

ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT)

NCT03759340

COMPLETED Phase 3

Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03687372

COMPLETED Phase 3

A Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03691831

COMPLETED Phase 2

A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis

NCT03585296

COMPLETED Phase 2

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

NCT03594227

COMPLETED Phase 2

Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata

NCT03551821

COMPLETED Phase 2

A Study in Male and Female Subjects With Androgenetic Alopecia Treated With ATI-50002 Topical Solution

NCT03495817

COMPLETED Phase 4

An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses

NCT03487588

COMPLETED Phase 2

A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo

NCT03468855

COMPLETED Phase 2

Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Universalis (AU) and Alopecia Totalis (AT)

NCT03315689

COMPLETED Phase 4

Safety and Tolerability of Oxymetazoline and Energy-Based Therapy in Participants With Rosacea

NCT03380390

TERMINATED Phase 2

A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata

NCT03354637

COMPLETED Phase 2

A Phase2 of A-101 Topical Solution in Subjects With Common Warts

NCT03210337

COMPLETED Phase 2

A Study of A-101 Topical Solution Administered Twice a Week in Subjects With Common Warts

NCT03278028

COMPLETED Phase 2

A Study of A-101 Topical Solution in Subjects With Dermatosis Papulosa Nigra

NCT03224598

COMPLETED Phase 2

A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis

NCT03148691

COMPLETED Phase 3

A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis

NCT02667275

COMPLETED Phase 3

A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.

NCT02667236

COMPLETED Phase 3

An Open-Label Safety Study of A-101 Solution

NCT02667288

COMPLETED Phase 2

A Study of A-101 Solution in Subjects With Common Warts.

NCT02669862

COMPLETED Phase 2

Study of A-101 for the Treatment of Seborrheic Keratosis

NCT02260180

COMPLETED Phase 2

Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis

NCT02160626

COMPLETED Phase 1

Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis

NCT01986920

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 24
Phase 3 6
Phase 4 2

What is open in the Aclaris Therapeutics pipeline

1 recruiting of 33 indexed (3% open); 28 completed (85%).

Phase mix: 8 late (III/IV) vs 25 early (I/II) (early-phase heavy).

Top condition: Common Wart (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Aclaris Therapeutics: open-pipeline peers nationwide

Peers matched on 33 registered trials and 3% open enrollment, not the therapeutic-area sidebar.

Aclaris Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 0%5%10%15%20% Total trials Recruiting share Aclaris TherapeuticsAntonios LikourezosBaylor UniversityBecton, Dickinson and CompanyCentocorSarepta TherapeuticsNational Center for Complementary and Integrative Health (NCCIH)Idorsia PharmaceuticalsKlein Buendel
Aclaris Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Aclaris Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 33 trials (± recruiting share)

Sponsors near 3% open enrollment (± trial volume)

What to do with this Aclaris Therapeutics page

33 registered trials is a research-attention snapshot, not an endorsement of Aclaris Therapeutics or any single study.

  • 1 of Aclaris Therapeutics's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Common Wart is the condition Aclaris Therapeutics studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Common Wart trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Aclaris Therapeutics pipeline card: 33 registered trials from official public datasets.Report a data error.