Aclaris Therapeutics

33 total trials 1 currently recruiting 28 completed

Aclaris Therapeutics sponsors 33 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 28 completed. 8 of these trials are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Common Wart, with 2 trials.

Trial Pipeline

33 total, page 1 of 1

RECRUITING Phase 2

ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis

NCT07011706

COMPLETED Phase 2

Study of ATI-2138 in Adult Participants With Moderate to Severe Atopic Dermatitis

NCT06585202

TERMINATED Phase 2

Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis

NCT05511519

COMPLETED Phase 2

Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Dermatitis

NCT05432596

COMPLETED Phase 2

ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)

NCT05279417

COMPLETED Phase 2

ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)

NCT05216224

TERMINATED Phase 2

Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS)

NCT04524858

COMPLETED Phase 2

Study of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis

NCT04598269

COMPLETED Phase 2

Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA

NCT04247815

COMPLETED Phase 3

Safety Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03812510

TERMINATED Phase 2

ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT)

NCT03759340

COMPLETED Phase 3

Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03687372

COMPLETED Phase 3

A Study of A-101 Topical Solution for the Treatment of Common Warts

NCT03691831

COMPLETED Phase 2

A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis

NCT03585296

COMPLETED Phase 2

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

NCT03594227

COMPLETED Phase 2

Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata

NCT03551821

COMPLETED Phase 2

A Study in Male and Female Subjects With Androgenetic Alopecia Treated With ATI-50002 Topical Solution

NCT03495817

COMPLETED Phase 4

An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses

NCT03487588

COMPLETED Phase 2

A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo

NCT03468855

COMPLETED Phase 2

Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Universalis (AU) and Alopecia Totalis (AT)

NCT03315689

COMPLETED Phase 4

Safety and Tolerability of Oxymetazoline and Energy-Based Therapy in Participants With Rosacea

NCT03380390

TERMINATED Phase 2

A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata

NCT03354637

COMPLETED Phase 2

A Phase2 of A-101 Topical Solution in Subjects With Common Warts

NCT03210337

COMPLETED Phase 2

A Study of A-101 Topical Solution Administered Twice a Week in Subjects With Common Warts

NCT03278028

COMPLETED Phase 2

A Study of A-101 Topical Solution in Subjects With Dermatosis Papulosa Nigra

NCT03224598

COMPLETED Phase 2

A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis

NCT03148691

COMPLETED Phase 3

A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis

NCT02667275

COMPLETED Phase 3

A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.

NCT02667236

COMPLETED Phase 3

An Open-Label Safety Study of A-101 Solution

NCT02667288

COMPLETED Phase 2

A Study of A-101 Solution in Subjects With Common Warts.

NCT02669862

COMPLETED Phase 2

Study of A-101 for the Treatment of Seborrheic Keratosis

NCT02260180

COMPLETED Phase 2

Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis

NCT02160626

COMPLETED Phase 1

Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis

NCT01986920

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 24
Phase 3 6
Phase 4 2

What the Pipeline for Aclaris Therapeutics Shows

According to the ClinicalTrials.gov registry, Aclaris Therapeutics is linked to 33 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 3% of the sponsor's indexed portfolio, and 28 are already marked complete, representing roughly 85% of the total.

The phase mix for Aclaris Therapeutics reports 8 late-stage studies (Phase 3 and Phase 4 combined) and 25 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Aclaris Therapeutics is Common Wart with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.