Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06848946 · ClinicalTrials.gov registry record · Phase 4
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
A Phase 4 study of Glaucoma Open-Angle and Phacoemulsification Cataract Surgery, sponsored by Glaukos Corporation.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 132
- Enrollment target
- 1
- Study location
NCT06848946: Recruiting Phase 4 study of Glaucoma Open-Angle and Phacoemulsification Cataract Surgery, sponsored by Glaukos Corporation.
NCT06848946 is a Phase 4 study of Glaucoma Open-Angle and Phacoemulsification Cataract Surgery that is actively recruiting participants, run by Glaukos Corporation. The registered enrollment target is 132 participants, below the 159-participant average among 22 other Glaucoma Open-Angle trials with a reported enrollment target (17% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06848946, a Phase 4 study of Glaucoma Open-Angle and Phacoemulsification Cataract Surgery, is actively recruiting participants, sponsored by Glaukos Corporation.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 132 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial will evaluate the safety and IOP -lowering efficacy of administering an iDose TR (travoprost intracameral implant) in conjunction with cataract surgery compared to cataract surgery alone
Primary Outcome
Mean diurnal IOP at the Month 3 Visit minus mean diurnal IOP at the Baseline Visit
Conditions Studied
Interventions
- COMBINATION_PRODUCT iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgery
- PROCEDURE Sham procedure in conjunction with cataract surgery
Study Locations (1)
Wisconsin
- Glaukos Investigator Site - Kenosha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2025-01-13 |
| Est. Completion | 2027-06 |
| Phase | Phase 4 |
What NCT06848946 shows while recruiting
NCT06848946 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 159-participant average among 22 other Glaucoma Open-Angle trials with a reported enrollment target (17% lower).
The record links to 3 conditions, with Glaucoma Open-Angle appearing as the primary indexed condition, and to 2 interventions - of which iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgery is the first listed.
NCT06848946 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06848946 about?
NCT06848946 is a clinical study titled "Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone". This trial will evaluate the safety and IOP -lowering efficacy of administering an iDose TR (travoprost intracameral implant) in conjunction with cataract surgery compared to cataract surgery alone
What is the current status of trial NCT06848946?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 132 participants. The study started on 2025-01-13. Estimated completion is 2027-06.
What conditions does trial NCT06848946 study?
This clinical trial studies the following conditions: Glaucoma Open-Angle, Phacoemulsification Cataract Surgery, Ocular Hypertension (OHT).
What interventions are being tested in trial NCT06848946?
The interventions under investigation include: iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgery (COMBINATION_PRODUCT), Sham procedure in conjunction with cataract surgery (PROCEDURE).
Who is sponsoring clinical trial NCT06848946?
This trial is sponsored by Glaukos Corporation, which has 33 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06848946 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glaucoma Open-Angle
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06848946's enrollment target sits among peer trials
132 10th of 22 higher than 13 of 22 other Glaucoma Open-Angle trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glaucoma Open-Angle trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Use of Methazolamide to Lower Intraocular Pressure
ACTIVE NOT RECRUITING · Phase 4
-
Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension
COMPLETED · Phase 4
-
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
RECRUITING
-
Electrical Stimulation for Vision Neuroenhancement in Glaucoma
RECRUITING · NA
-
Electrical Stimulation for the Treatment of Optic Neuropathies
RECRUITING · NA
-
Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone
RECRUITING · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01766297 · 132 participants · Phase 2
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
- NCT04002947 · 132 participants · Phase 2
Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma
- NCT04128189 · 132 participants · Phase 3
Shingrix in Renal Transplant Recipients
- NCT04199780 · 132 participants · NA
Effects of tDCS Combined With CBI on Postsurgical Pain
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI