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Glaucoma Open-Angle: later-stage trial registry
11 of 24 indexed Glaucoma Open-Angle trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #686 of 28,707 conditions by registered trial count.
24 US clinical trials · 11 currently recruiting · #686 of 28,707 conditions by registered trial count
Glaucoma Open-Angle: 24 US clinical trials tracked, 11 recruiting.
Glaucoma Open-Angle is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Glaukos Corporation, running 4 of these trials.
Enrollment posture brief
Registry condition glaucoma-open-angle
OPEN 11 | RECR 46% | LATE 8 | EARLY 3 | RANK #686 | SPON 4
Volume-matched condition peers
Nearest open-share peer: High Blood Pressure (46% recruiting · 24 trials)
Glaucoma Open-Angle lists 11 open slots (46% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Glaucoma Open-Angle on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Glaucoma Open-Angle is recruiting above its size-band peers.
11 of 24 indexed trials (45.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Glaucoma Open-Angle research.
Glaukos Corporation accounts for 4 of 24 trials (16.7%). 18 distinct sponsors appear on at least one study for this condition label.
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Typical Glaucoma Open-Angle enrolment sits around 125 participants.
Median target enrolment is 125 among the 23 trials that report a genuine target (sentinel values excluded). 11 of those (47.8%) plan for fewer than 100 participants.
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Glaucoma Open-Angle research is mostly interventional.
21 interventional and 3 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
24 total, page 1 of 1
A Trial of Hydrus Microstent Versus Goniotomy
Massachusetts Eye and Ear Infirmary
NCT06289491
Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone
Glaukos Corporation
NCT06066645
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Amneal Pharmaceuticals
NCT05401357
Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone
Glaukos Corporation
NCT06848946
Optic Nerve Head Strain as Biomarker for Glaucoma
Johns Hopkins University
NCT06240312
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
Smartlens
NCT06689696
Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension
PolyActiva Pty
NCT06964191
Electrical Stimulation for the Treatment of Glaucoma
Stanford University
NCT05626491
Electrical Stimulation for the Treatment of Optic Neuropathies
Stanford University
NCT05626426
Electrical Stimulation for Vision Neuroenhancement in Glaucoma
Stanford University
NCT06685211
Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery
Vold Vision P.L.L.C
NCT05624398
iStent Inject New Enrollment Post-Approval Study
Glaukos Corporation
NCT04624698
Clinical Outcomes in Cataract Surgery With OMNI Canaloplasty vs Cataract Surgery With OMNI Canaloplasty and Hydrus Stent
Ridge Eye Care
NCT05949242
Use of Methazolamide to Lower Intraocular Pressure
University of Colorado, Denver
NCT05498103
Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension
Allergan
NCT02247804
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%
Glaukos Corporation
NCT03519386
Pigment Dispersion Syndrome With and Without Glaucoma
National Eye Institute (NEI)
NCT00001152
Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension
Allergan
NCT01253902
Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma
Chicago Center for Vision Research
NCT00317577
A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System
Sight Sciences
NCT05044793
Negative Pressure Applied by the Equinox MPD for Severe Open Angle Glaucoma
Equinox
NCT04632329
Safety and Efficacy of a Glaucoma Drug Delivery System
Vistakon Pharmaceuticals
NCT00824720
Evaluating Home Testing Devices for the Management of Glaucoma
Wills Eye
NCT05325996
A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT)
Alcon Research
NCT00051155
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Glaucoma Open-Angle records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Glaucoma Open-Angle trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Glaucoma Open-Angle page
24 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Glaucoma Open-Angle trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Glaukos Corporation sponsors the most Glaucoma Open-Angle trials on record, review their full trial history before evaluating a specific study. See Glaukos Corporation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Glaucoma Open-Angle condition card totals 24 registered trials; most-linked intervention Repetitive, Transorbital Alternating Current Stimulation (rtACS); top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.