Gilead Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Gilead Sciences sits in the top decile of US sponsors by registered trial count (#71 of 15,742 sponsors by registered trial count).

504 total trials 26 currently recruiting 346 completed early-phase tilt top decile by trial count

Gilead Sciences: 504 sponsored US clinical trials, 26 recruiting.

Gilead Sciences sponsors 504 registered US clinical trials on ClinicalTrials.gov, 26 of them currently recruiting, and 346 completed. 164 of these trials are in Phase 3-4 (later-stage) and 317 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV-1-infection, with 20 trials.

Top-decile sponsor footprint

Gilead Sciences ranks in the top decile of sponsors by registered trial count (#71 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 34/100

346 of 445 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (77.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

504 total, page 9 of 11

COMPLETED Phase 3

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis and Chronic Burkholderia Species Infection

NCT01059565

COMPLETED Phase 2

Dose-Ranging Study of Sofosbuvir in Combination With Pegylated Interferon and Ribavirin in Treatment Naïve GT 1 HCV Patients

NCT01054729

COMPLETED Phase 2

Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of MBX-2982 Administered Daily for 4 Weeks as Monotherapy in Patients With Type 2 Diabetes

NCT01035879

COMPLETED Phase 2

Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United States

NCT00936715

TERMINATED Phase 3

ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis

NCT00879229

COMPLETED Phase 2

Safety and Efficacy of Cobicistat-boosted Atazanavir Compared to Ritonavir-boosted Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

NCT00892437

TERMINATED Phase 2

Efficacy and Safety Study of GS-9450 Treatment for 6 Months in Patients With Chronic Hepatitis C Virus Infection

NCT00874796

COMPLETED Phase 2

Study of the Safety and Efficacy of Stribild Versus Atripla in Human Immunodeficiency Virus, Type 1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

NCT00869557

TERMINATED Phase 2

Study of Cicletanine for Pulmonary Arterial Hypertension (PAH)

NCT00832507

TERMINATED Phase 4

Study of Ranexa in Patients With Coronary Artery Disease and Painful Polyneuropathy

NCT00832572

COMPLETED Phase 3

Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B Infection

NCT00734162

COMPLETED Phase 2

Evaluation of the Quality of Life Questionnaire-Bronchiectasis (QOL-B) in Patients With Bronchiectasis

NCT00805025

TERMINATED Phase 3

(ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF

NCT00768300

TERMINATED Phase 2

Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin

NCT00814372

COMPLETED Phase 3

Study of Ambrisentan in Participants With Pulmonary Hypertension

NCT00777920

COMPLETED Phase 2

Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection

NCT00794586

COMPLETED Phase 2

Safety, Tolerability, and Antiviral Activity of 24 or 48 Weeks of GS-9190 in Combination With Peginterferon Alfa 2a and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection

NCT00743795

COMPLETED Phase 3

Tenofovir Disoproxil Fumarate (Tenofovir DF) Versus Emtricitabine/Tenofovir DF in Subjects Resistant to Lamivudine

NCT00737568

COMPLETED Phase 2

Safety, Tolerability, Pharmacokinetics and Activity of GS-9450 in Adults With Non-Alcoholic Steatohepatitis (NASH)

NCT00740610

COMPLETED Phase 1

Phase I/II Study of Different Doses and Dose Schedules of Milatuzumab (hLL1) in CLL

NCT00603668

COMPLETED Phase 3

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

NCT00757237

COMPLETED Phase 4

A Study to Evaluate Tenofovir Disoproxil Fumarate (DF) in Asian-American Adults With Chronic Hepatitis B Infection

NCT00736190

COMPLETED Phase 4

Safety and Efficacy Study of Switching From Epzicom to Truvada

NCT00724711

COMPLETED Phase 3

Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Elvitegravir Versus Raltegravir

NCT00708162

COMPLETED Phase 1

Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies

NCT00710528

COMPLETED Phase 3

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa

NCT00712166

COMPLETED Phase 4

Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1)

NCT00617305

COMPLETED Phase 2

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV

NCT00725803

COMPLETED Phase 2

Safety Study of Tecadenoson to Treat Atrial Fibrillation

NCT00713401

COMPLETED Phase 1

Ph I/II Study of Subcutaneously Administered Veltuzumab (hA20) in NHL and CLL

NCT00546793

COMPLETED Phase 1

Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer

NCT00603863

COMPLETED Phase 4

An Open-label, Multi-center Study Evaluating the Validity, Reliability, and Responsiveness of a New Female-specific Angina Questionnaire in Women With Chronic Angina Treated With Ranolazine Extended-release Tablets (CVT 3041)

NCT00644332

TERMINATED Phase 1

Study of Veltuzumab (hA20) at Different Doses in Patients With ITP

NCT00547066

COMPLETED Phase 2

Truvada Versus Truvada Plus Hepatitis B Immunoglobulin (HBIg) in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant

NCT00507689

COMPLETED

Fanconi Syndrome Due to ARVs in HIV-Infected Persons

NCT00499187

COMPLETED Phase 2

A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)

NCT00507507

COMPLETED Phase 1

Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts

NCT00499967

COMPLETED Phase 2

Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol

NCT00701883

TERMINATED Phase 1

A Trial of GS-9219 in Chronic Lymphocytic Leukemia (CLL), Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM)

NCT00499239

TERMINATED Phase 3

DORADO-AC-EX - A Long-Term Safety Extension Study to the Phase 3 DORADOC-AC Study (Protocol DAR-312) of Darusentan in Resistant Hypertension

NCT00389675

COMPLETED Phase 2

Safety of EVG+RTV Administered With Other Antiretroviral Agents for the Treatment of HIV-1 Infection

NCT00445146

COMPLETED Phase 1

Phase Ib Study of SC Milatuzumab in SLE

NCT01845740

COMPLETED Phase 1

Phase I/II Study of hLL1 in Multiple Myeloma

NCT00421525

COMPLETED Phase 3

Safety and Efficacy of Switching From Stavudine or Zidovudine to Tenofovir DF in HIV-1 Infected Children

NCT00528957

COMPLETED Phase 2

Safety and Tolerability Study of MBX-2044 in Patients With Type 2 Diabetes

NCT00422487

COMPLETED Phase 3

DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension

NCT00389779

TERMINATED Phase 3

DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension

NCT00353574

COMPLETED Phase 3

Safety and Efficacy Study of Ambrisentan in Subjects With Pulmonary Hypertension

NCT00380068

COMPLETED Phase 4

Single Tablet Regimen (STR) Simplification Study for HIV-1 Infected Patients

NCT00365612

COMPLETED Phase 3

DORADO - Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension

NCT00330369

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What is open in the Gilead Sciences pipeline

26 recruiting of 504 indexed (5% open); 346 completed (69%).

Phase mix: 164 late (III/IV) vs 317 early (I/II) (early-phase heavy).

Top condition: HIV-1-infection (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Gilead Sciences: open-pipeline peers nationwide

Peers matched on 504 registered trials and 5% open enrollment, not the therapeutic-area sidebar.

Gilead Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20% Total trials Recruiting share Gilead SciencesH. Lee Moffitt Cancer Center and Research InstituteNational Heart, Lung, and Blood Institute (NHLBI)Boehringer IngelheimNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Creighton UniversityAlmirall, S.A.Cordis USDefense and Veterans Center for Integrative Pain Management
Gilead Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Gilead Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 504 trials (± recruiting share)

Sponsors near 5% open enrollment (± trial volume)

What to do with this Gilead Sciences page

504 registered trials is a research-attention snapshot, not an endorsement of Gilead Sciences or any single study.

  • 26 of Gilead Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV-1-infection is the condition Gilead Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV-1-infection trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Gilead Sciences pipeline card: 504 registered trials from official public datasets.Report a data error.