Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Safety and Efficacy Study of Switching From Epzicom to Truvada
NCT00724711 · View on ClinicalTrials.gov ↗
Study Summary
This protocol describes a prospective, randomized, open-label, multicenter study to evaluate the safety and efficacy of switching from fixed dose abacavir (ABC)/lamivudine (3TC) to fixed dose emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in virologically suppressed, human immunodeficiency virus type 1 (HIV-1) infected subjects maintained on a ritonavir-boosted protease inhibitor (PI/r)-containing antiretroviral (ARV) regimen. Duration of treatment is 48 weeks.
Conditions Studied
Interventions
- DRUG emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF)
- DRUG abacavir (ABC)/lamivudine (3TC)
Study Locations (20)
California
- Vista Medical Partners — Beverly Hills
- AHF — Beverly Hills
- Pacific Oaks Medical Group — Beverly Hills
- Center for Special Immunology — Fountain Valley
- Living Hope Clinical Foundation — Long Beach
- Jeffrey Goodman Special Care Clinic — Los Angeles
- Peter J. Ruane, MD, Inc. — Los Angeles
- Anthony M Mills, MD — Los Angeles
- Orange Coast Medical Group — Newport Beach
- Tarzana Treatment Center — Northridge
- Alameda County Medical Center — Oakland
- Health Management Institute, Inc. — San Francisco
- Metropolis Medical — San Francisco
Florida
- Biogenomx Research Institute, LLC — Fort Lauderdale
- Life Way Inc. — Fort Lauderdale
- Therafirst Medical Centers — Fort Lauderdale
- HIV Clinical Research — Fort Lauderdale
Arkansas
- Health For Life Clinic, PLLC — Little Rock
Colorado
- Kaiser Permanente — Denver
Connecticut
- Blick Medical Associates — Norwalk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 312 participants |
| Start Date | 2008-07 |
| Est. Completion | 2011-04 |
| Phase | Phase 4 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00724711
The ClinicalTrials.gov registry entry for NCT00724711 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 312 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with HIV Infection appearing as the primary indexed condition, and to 2 interventions — of which emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00724711 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Florida, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00724711 about?
NCT00724711 is a clinical study titled "Safety and Efficacy Study of Switching From Epzicom to Truvada". This protocol describes a prospective, randomized, open-label, multicenter study to evaluate the safety and efficacy of switching from fixed dose abacavir (ABC)/lamivudine (3TC) to fixed dose emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in virologically suppressed, human immunodeficiency ...
What is the current status of trial NCT00724711?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 312 participants. The study started on 2008-07. Estimated completion is 2011-04.
What conditions does trial NCT00724711 study?
This clinical trial studies the following conditions: HIV Infection. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00724711?
The interventions under investigation include: emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) (DRUG), abacavir (ABC)/lamivudine (3TC) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00724711?
This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00724711 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.