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NCT00768300 · ClinicalTrials.gov registry record · Phase 3

(ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF

A Phase 3 study, sponsored by Gilead Sciences.

Terminated
Registry status
Phase 3
Development phase
494
Enrollment target

NCT00768300 is a Phase 3 study that was terminated before completion, run by Gilead Sciences. The registered enrollment target is 494 participants.

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The verdict

NCT00768300, a Phase 3 study, was terminated before completion, sponsored by Gilead Sciences.

TERMINATED
Registry status
Phase 3
Development phase
494 participants
Enrollment target

Study Summary

The ARTEMIS-IPF study was conducted to determine if ambrisentan was effective in delaying disease progression and death in participants with idiopathic pulmonary fibrosis (IPF), to evaluate its safety, and to evaluate its effect on development of pulmonary hypertension, quality of life, and dyspnea (shortness of breath) symptoms in this participant population. Participants were randomized in a 2:1 ratio to receive ambrisentan or placebo, respectively. Participation in the study was to be up to 4 years, depending on how long it would take to enroll participants and observe study events. After randomization, visits to the clinic took place every 3 months, and laboratory procedures were performed every month.

Interventions

  • DRUG Placebo
  • DRUG Ambrisentan

Trial Details

FieldValue
Enrollment Target 494 participants
Start Date 2008-12
Est. Completion 2011-02
Phase Phase 3

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT00768300

The ClinicalTrials.gov registry entry for NCT00768300 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 494 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00768300 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00768300 about?

NCT00768300 is a clinical study titled "(ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF". The ARTEMIS-IPF study was conducted to determine if ambrisentan was effective in delaying disease progression and death in participants with idiopathic pulmonary fibrosis (IPF), to evaluate its safety, and to evaluate its effect on development of pulmonary hypertension, quality of life, and dyspnea ...

What is the current status of trial NCT00768300?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 494 participants. The study started on 2008-12. Estimated completion is 2011-02.

What interventions are being tested in trial NCT00768300?

The interventions under investigation include: Placebo (DRUG), Ambrisentan (DRUG).

Who is sponsoring clinical trial NCT00768300?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.